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dc.contributor.authorPinos, Helena
dc.contributor.authorCarrillo, Beatriz
dc.contributor.authorMerchán, Ana
dc.contributor.authorBiosca-Brull, Judit
dc.contributor.authorPérez-Fernández, Cristian
dc.contributor.authorColomina, María Teresa
dc.contributor.authorSánchez-Santed, Fernando
dc.contributor.authorMartin-Sanchez, Fernando 
dc.contributor.authorCollado, Paloma
dc.contributor.authorArias, Jorge L
dc.contributor.authorConejo, Nélida M
dc.date.accessioned2022-04-19T12:53:02Z
dc.date.available2022-04-19T12:53:02Z
dc.date.issued2021-07-04
dc.identifier.citationInt J Environ Res Public Health. 2021;18(13):7170.es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/14113
dc.description.abstractIn recent years, the worldwide prevalence of overweight and obesity among adults and children has dramatically increased. The conventional model regarding the onset of obesity is based on an imbalance between energy intake and expenditure. However, other possible environmental factors involved, such as the exposure to chemicals like pesticides, cannot be discarded. These compounds could act as endocrine-disrupting chemicals (EDC) that may interfere with hormone activity related to several mechanisms involved in body weight control. The main objective of this study was to systematically review the data provided in the scientific literature for a possible association between prenatal and postnatal exposure to pesticides and obesity in offspring. A total of 25 human and 9 animal studies were analyzed. The prenatal, perinatal, and postnatal exposure to organophosphate, organochlorine, pyrethroid, neonicotinoid, and carbamate, as well as a combined pesticide exposure was reviewed. This systematic review reveals that the effects of pesticide exposure on body weight are mostly inconclusive, finding conflicting results in both humans and experimental animals. The outcomes reviewed are dependent on many factors, including dosage and route of administration, species, sex, and treatment duration. More research is needed to effectively evaluate the impact of the combined effects of different pesticides on human health.es_ES
dc.description.sponsorshipThis study was supported by grants from the Spanish Government (Ministerio de Economía y Competitividad and Instituto Mixto de Investigación-Escuela Nacional de Sanidad (IMIENS)) and the Fondo Europeo de Desarrollo Regional (MINECO-FEDER) Grant numbers: PSI2017-90806-REDT, PSI2017-83038-P, PSI2017-83893-R, PSI2017-86396-P, PSI2017-86847-C2-2-R MINECO-FEDER, and IMIENS: PIC-IMIENS-2018-003.es_ES
dc.language.isoenges_ES
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI) es_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectCarbamateses_ES
dc.subjectChlorpyrifoses_ES
dc.subjectNeonicotinoidses_ES
dc.subjectObesityes_ES
dc.subjectOrganochlorinees_ES
dc.subjectOrganophosphatees_ES
dc.subjectPesticideses_ES
dc.subjectPyrethroidses_ES
dc.titleRelationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Reviewes_ES
dc.typeArtículoes_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID34281107es_ES
dc.format.volume18es_ES
dc.format.number13es_ES
dc.format.page7170es_ES
dc.identifier.doi10.3390/ijerph18137170es_ES
dc.contributor.funderEuropean Regional Development Fund es_ES
dc.contributor.funderMinisterio de Economía y Competitividad (España)es_ES
dc.contributor.funderInstituto de Salud Carlos III es_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1660-4601es_ES
dc.relation.publisherversionhttps://doi.org/10.3390/ijerph18137170es_ES
dc.identifier.journalInternational Journal of Environmental Research And Public Healthes_ES
dc.repisalud.centroISCIII::Escuela Nacional de Sanidades_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.relation.projectFECYTinfo:eu-repo/grantAgreement/ES/PSI2017-90806-REDTes_ES
dc.relation.projectFECYTinfo:eu-repo/grantAgreement/ES/PSI2017-83038-Pes_ES
dc.relation.projectFECYTinfo:eu-repo/grantAgreement/ES/PSI2017-83893-Res_ES
dc.relation.projectFECYTinfo:eu-repo/grantAgreement/ES/PSI2017-86396-Pes_ES
dc.relation.projectFECYTinfo:eu-repo/grantAgreement/ES/PSI2017-86847-C2-2-Res_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PIC-IMIENS-2018-003es_ES


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