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dc.contributor.author | Pinos, Helena | |
dc.contributor.author | Carrillo, Beatriz | |
dc.contributor.author | Merchán, Ana | |
dc.contributor.author | Biosca-Brull, Judit | |
dc.contributor.author | Pérez-Fernández, Cristian | |
dc.contributor.author | Colomina, María Teresa | |
dc.contributor.author | Sánchez-Santed, Fernando | |
dc.contributor.author | Martin-Sanchez, Fernando | |
dc.contributor.author | Collado, Paloma | |
dc.contributor.author | Arias, Jorge L | |
dc.contributor.author | Conejo, Nélida M | |
dc.date.accessioned | 2022-04-19T12:53:02Z | |
dc.date.available | 2022-04-19T12:53:02Z | |
dc.date.issued | 2021-07-04 | |
dc.identifier.citation | Int J Environ Res Public Health. 2021;18(13):7170. | es_ES |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/14113 | |
dc.description.abstract | In recent years, the worldwide prevalence of overweight and obesity among adults and children has dramatically increased. The conventional model regarding the onset of obesity is based on an imbalance between energy intake and expenditure. However, other possible environmental factors involved, such as the exposure to chemicals like pesticides, cannot be discarded. These compounds could act as endocrine-disrupting chemicals (EDC) that may interfere with hormone activity related to several mechanisms involved in body weight control. The main objective of this study was to systematically review the data provided in the scientific literature for a possible association between prenatal and postnatal exposure to pesticides and obesity in offspring. A total of 25 human and 9 animal studies were analyzed. The prenatal, perinatal, and postnatal exposure to organophosphate, organochlorine, pyrethroid, neonicotinoid, and carbamate, as well as a combined pesticide exposure was reviewed. This systematic review reveals that the effects of pesticide exposure on body weight are mostly inconclusive, finding conflicting results in both humans and experimental animals. The outcomes reviewed are dependent on many factors, including dosage and route of administration, species, sex, and treatment duration. More research is needed to effectively evaluate the impact of the combined effects of different pesticides on human health. | es_ES |
dc.description.sponsorship | This study was supported by grants from the Spanish Government (Ministerio de Economía y Competitividad and Instituto Mixto de Investigación-Escuela Nacional de Sanidad (IMIENS)) and the Fondo Europeo de Desarrollo Regional (MINECO-FEDER) Grant numbers: PSI2017-90806-REDT, PSI2017-83038-P, PSI2017-83893-R, PSI2017-86396-P, PSI2017-86847-C2-2-R MINECO-FEDER, and IMIENS: PIC-IMIENS-2018-003. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | es_ES |
dc.type.hasVersion | VoR | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Carbamates | es_ES |
dc.subject | Chlorpyrifos | es_ES |
dc.subject | Neonicotinoids | es_ES |
dc.subject | Obesity | es_ES |
dc.subject | Organochlorine | es_ES |
dc.subject | Organophosphate | es_ES |
dc.subject | Pesticides | es_ES |
dc.subject | Pyrethroids | es_ES |
dc.title | Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review | es_ES |
dc.type | journal article | es_ES |
dc.rights.license | Atribución 4.0 Internacional | * |
dc.identifier.pubmedID | 34281107 | es_ES |
dc.format.volume | 18 | es_ES |
dc.format.number | 13 | es_ES |
dc.format.page | 7170 | es_ES |
dc.identifier.doi | 10.3390/ijerph18137170 | es_ES |
dc.contributor.funder | Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF) | es_ES |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | es_ES |
dc.contributor.funder | Instituto de Salud Carlos III | es_ES |
dc.description.peerreviewed | Sí | es_ES |
dc.identifier.e-issn | 1660-4601 | es_ES |
dc.relation.publisherversion | https://doi.org/10.3390/ijerph18137170 | es_ES |
dc.identifier.journal | International Journal of Environmental Research And Public Health | es_ES |
dc.repisalud.centro | ISCIII::Escuela Nacional de Sanidad | es_ES |
dc.repisalud.institucion | ISCIII | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/PSI2017-90806-REDT | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/PSI2017-83038-P | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/PSI2017-83893-R | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/PSI2017-86396-P | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/PSI2017-86847-C2-2-R | es_ES |
dc.relation.projectFIS | info:eu-repo/grantAgreement/ES/PIC-IMIENS-2018-003 | es_ES |