Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/12456
Lower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count.
J Microbiol Immunol Infect . 2019 Aug;52(4):667-671.
Exosome-derived miR-21 was independently associated with CD4 T cell decline in HIV-1-infected elite controllers (OR 0.369, 95% CI 0.137-0.994, p = 0.049). Also, a negative correlation between miR-21 expression and MCP-1 level was found (r = -0.649, p = 0.020), while no correlation between soluble biomarkers or cellular immune activation was found.
Exosomes | Adult | Biomarkers | CD4 Lymphocyte Count | CD4-Positive T-Lymphocytes | Chemokine CCL2 | Cross-Sectional Studies | Female | HIV Infections | HIV-1 | Humans | Male | MicroRNAs | Middle Aged | Plasma
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