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dc.contributor.authorInfantes-Lorenzo, Jose Antonio 
dc.contributor.authorRomero, B
dc.contributor.authorRodríguez-Bertos, A
dc.contributor.authorRoy, A
dc.contributor.authorOrtega, J
dc.contributor.authorde Juan, Lucía
dc.contributor.authorMoreno-Iruela, Inmaculada 
dc.contributor.authorDominguez-Rodriguez, Mercedes 
dc.contributor.authorDomínguez, L
dc.contributor.authorBezos, J
dc.date.accessioned2021-02-02T08:24:40Z
dc.date.available2021-02-02T08:24:40Z
dc.date.issued2020-11-10
dc.identifier.citationBMC Vet Res . 2020 Nov 10;16(1):435.es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/11771
dc.description.abstractAnimal tuberculosis (TB) is distributed worldwide and has a wide range of wild and domestic reservoirs. Few studies concerning TB in camelids have been published in the last decade, particularly as regards Old World Camelids (OWC), but the increase in reports of TB outbreaks in these species in recent years suggests a high susceptibility to the infection. We studied a dromedary camel (Camelus dromedarius) herd (n = 24) in which a Mycobacterium caprae infection was detected. The TB infection was confirmed in one animal at necropsy through the detection of TB lesions, mainly in the abdominal organs, and the subsequent isolation of M. caprae (SB0157 spoligotype). The whole herd was additionally tested using cellular and humoral based diagnostic techniques. The intradermal tuberculin test results were compared with those obtained using P22 ELISA for the detection of specific antibodies against the M. tuberculosis complex. The TB infected animal was a positive reactor to both the intradermal tuberculin tests and P22 ELISA, while the others were negative to all the diagnostic tests. The present study found M. caprae infection in OWC. This is the first report of M. caprae infection in an OWC not living in a zoo. Since the animal was born in the herd and fed with goat's milk, this practice was suspected to be the potential source of TB infection, which was not confirmed in the other animals present in the herd. Moreover, our results highlight that the intradermal tuberculin test and the P22 ELISA could be valuable tools for the diagnosis of TB in OWC.es_ES
dc.description.sponsorshipAlvaro Roy is the recipient of an Industrial Doctorate contract (DI-15-08110) funded by the Spanish Ministry of Economy, Industry and Competitiveness (MINECO) and the European Social Fund. This contract finances the realisation of a doctoral thesis related to the diagnosis of tuberculosis in domestic animals, and his experience was essential during the revision of the manuscript.es_ES
dc.language.isoenges_ES
dc.publisherBMCes_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectAnimal tuberculosises_ES
dc.subjectDiagnostic testses_ES
dc.subjectMycobacterium capraees_ES
dc.subjectOld World Camelidses_ES
dc.subjectPathologyes_ES
dc.titleTuberculosis caused by Mycobacterium caprae in a camel (Camelus dromedarius).es_ES
dc.typeArtículoes_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID33172453es_ES
dc.format.volume16es_ES
dc.format.number1es_ES
dc.format.page435es_ES
dc.identifier.doi10.1186/s12917-020-02665-0es_ES
dc.contributor.funderMinisterio de Economía, Industria y Competitividad (España)
dc.contributor.funderEuropean Union
dc.description.peerreviewedes_ES
dc.identifier.e-issn1746-6148es_ES
dc.relation.publisherversionhttps://doi.org/10.1186/s12917-020-02665-0es_ES
dc.identifier.journalBMC veterinary researches_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/DI-15-08110es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Atribución 4.0 Internacional
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