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dc.contributor.authorWorking group for the surveillance and control of COVID-19 in Spain
dc.contributor.authorPozo Sanchez, Francisco 
dc.contributor.authorCasas Flecha, Inmaculada 
dc.contributor.authorPeñalver-Argüeso, Belén 
dc.contributor.authorPampaka, Despina 
dc.contributor.authorOliva Dominguez, Jesus Angel 
dc.contributor.authorSastre García, María 
dc.contributor.authorLarrauri, Amparo 
dc.date.accessioned2020-12-30T09:28:03Z
dc.date.available2020-12-30T09:28:03Z
dc.date.issued2020-12
dc.identifier.citationEuro Surveill. 2020 Dec;25(50):2001431.es_ES
dc.identifier.otherhttp://hdl.handle.net/10668/16815
dc.identifier.urihttp://hdl.handle.net/20.500.12105/11572
dc.description.abstractBackground: The first wave of the coronavirus disease (COVID-19) pandemic spread rapidly in Spain, one of Europe's most affected countries. A national lockdown was implemented on 15 March 2020. Aim: To describe reported cases and the impact of national lockdown, and to identify disease severity risk factors. Methods: National surveillance data were used to describe PCR-confirmed cases as at 27 April 2020. We compared case characteristics by severity categories (hospitalisation, admission to intensive care unit (ICU), death) and identified severity risk factors using multivariable regression. Results: The epidemic peaked on 20 March. Of 218,652 COVID-19 cases, 45.4% were hospitalised, 4.6% were admitted to ICU and 11.9% died. Among those who died, 94.8% had at least one underlying disease. Healthcare workers (HCWs) represented 22.9% of cases. Males were more likely to have severe outcomes than females. Cardiovascular disease was a consistent risk factor. Patients with pneumonia had higher odds of hospitalisation (odds ratio (OR): 26.63; 95% confidence interval (CI): 25.03-28.33). The strongest predictor of death was age ≥ 80 years (OR: 28.4; 95% CI: 19.85-40.78). Among underlying diseases, chronic renal disease had highest odds of death (OR: 1.47; 95% CI: 1.29-1.68). Conclusions: COVID-19 case numbers began declining 6 days after the national lockdown. The first wave of the COVID-19 pandemic in Spain had a severe impact on elderly people. Patients with cardiovascular or renal conditions were at higher risk for severe outcomes. A high proportion of cases were HCWs. Enhanced surveillance and control measures in these subgroups are crucial during future COVID-19 waves.es_ES
dc.language.isoenges_ES
dc.publisherEuropean Centre for Disease Prevention and Control (ECDC) es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.meshPandemics es_ES
dc.subject.meshSARS-CoV-2es_ES
dc.subject.meshAdolescent es_ES
dc.subject.meshAdult es_ES
dc.subject.meshAged es_ES
dc.subject.meshAged, 80 and over es_ES
dc.subject.meshAlgorithms es_ES
dc.subject.meshCOVID-19es_ES
dc.subject.meshChild es_ES
dc.subject.meshChild, Preschool es_ES
dc.subject.meshCommunicable Disease Control es_ES
dc.subject.meshComorbidity es_ES
dc.subject.meshData Collection es_ES
dc.subject.meshFemale es_ES
dc.subject.meshGeography, Medical es_ES
dc.subject.meshHealth Personnel es_ES
dc.subject.meshHumans es_ES
dc.subject.meshInfant es_ES
dc.subject.meshMale es_ES
dc.subject.meshMiddle Aged es_ES
dc.subject.meshPhysical Distancinges_ES
dc.subject.meshPopulation Surveillance es_ES
dc.subject.meshQuarantine es_ES
dc.subject.meshRegistries es_ES
dc.subject.meshRisk Factors es_ES
dc.subject.meshSpain es_ES
dc.subject.meshYoung Adult es_ES
dc.titleThe first wave of the COVID-19 pandemic in Spain: characterisation of cases and risk factors for severe outcomes, as at 27 April 2020es_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.format.volume25es_ES
dc.format.number50es_ES
dc.identifier.doi10.2807/1560-7917.ES.2020.25.50.2001431es_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1025-496X
dc.relation.publisherversionhttp://dx.doi.org/10.2807/1560-7917.ES.2020.25.50.2001431es_ES
dc.identifier.journalEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletines_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemiologíaes_ES
dc.repisalud.centroISCIII::Escuela Nacional de Sanidades_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiología
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES


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Atribución 4.0 Internacional
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