Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/11524
Enteroviruses in Spain: virological and epidemiological studies over 10 years (1988-97)
Trallero, Gloria ISCIII | Casas Flecha, Inmaculada ISCIII | Tenorio, Antonio ISCIII | Echevarria, Juan Emilio ISCIII | Castellanos-Nadal, Ana Maria ISCIII | Lozano, Alvaro ISCIII | Perez-Breña, Pilar ISCIII
Epidemiol Infect 2000 Jun;124(3):497-506.
A total of 15,662 clinical samples were analysed for enterovirus (EV) isolation in cell cultures during a 10-year period (1988-97). Furthermore, 210 isolates of EV obtained in primary laboratories within Spain from patients with meningitis were characterized. The total number of EV typed was 758, including 727 non-polio EV and 31 Sabin-like (SL) polioviruses. Twenty-eight EV serotypes were represented. Echoviruses comprised 90% (653/727) of fully typed non-polio EV. The four most prevalent serotypes were echovirus 30, echovirus 9, echovirus 6 and echovirus 4. Echovirus 30 was the main serotype associated with meningitis. Echovirus 9 was the aetiological agent in 20 outbreaks of meningitis while the occurrence of echovirus 6 was localized in 1 year (1997). Coxsackieviruses A and B occurred in 3 and 7% of the non-polio EV respectively. Coxsackievirus B5 presented the relative greater abundance. This paper examines the epidemiology of EV in Spain to serotype level over a 10-year period with special attention to non-polio EV associated with meningitis.
Disease Outbreaks | Adolescent | Adult | Aged | Child | Child, Preschool | Enterovirus Infections | Female | Humans | Incidence | Infant | Infant, Newborn | Male | Meningitis, Viral | Middle Aged | Retrospective Studies | Serotyping | Spain
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