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dc.contributor.authorNdumbi, Patricia
dc.contributor.authorFreidl, Gudrun S
dc.contributor.authorWilliams, Christopher J
dc.contributor.authorMårdh, Otilia
dc.contributor.authorVarela Martinez, Maria del Carmen 
dc.contributor.authorAvellón, Ana 
dc.contributor.authorFriesema, Ingrid
dc.contributor.authorVennema, Harry
dc.contributor.authorBeebeejaun, Kazim
dc.contributor.authorNgui, Siew Lin
dc.contributor.authorEdelstein, Michael
dc.contributor.authorSmith-Palmer, Alison
dc.contributor.authorMurphy, Niamh
dc.contributor.authorDean, Jonathan
dc.contributor.authorFaber, Mirko
dc.contributor.authorWenzel, Jürgen
dc.contributor.authorKontio, Mia
dc.contributor.authorMüller, Luise
dc.contributor.authorMidgley, Sofie Elisabeth
dc.contributor.authorSundqvist, Lena
dc.contributor.authorEderth, Josefine Lundberg
dc.contributor.authorRoque-Afonso, Anne-Marie
dc.contributor.authorCouturier, Elisabeth
dc.contributor.authorKlamer, Sofieke
dc.contributor.authorRebolledo, Javiera
dc.contributor.authorSuin, Vanessa
dc.contributor.authorAberle, Stephan W
dc.contributor.authorSchmid, Daniela
dc.contributor.authorDe Sousa, Rita
dc.contributor.authorAugusto, Gonçalo Figueiredo
dc.contributor.authorAlfonsi, Valeria
dc.contributor.authorDel Manso, Martina
dc.contributor.authorCiccaglione, Anna Rita
dc.contributor.authorMellou, Kassiani
dc.contributor.authorHadjichristodoulou, Christos
dc.contributor.authorDonachie, Alastair
dc.contributor.authorBorg, Maria-Louise
dc.contributor.authorSočan, Maja
dc.contributor.authorPoljak, Mario
dc.contributor.authorSeveri, Ettore
dc.date.accessioned2020-11-17T13:28:51Z
dc.date.available2020-11-17T13:28:51Z
dc.date.issued2018
dc.identifier.citationEuropean Centre for Disease Prevention and Controles_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/11358
dc.description.abstractBetween 1 June 2016 and 31 May 2017, 17 European Union (EU) and European Economic Area countries reported 4,096 cases associated with a multi-country hepatitis A (HA) outbreak. Molecular analysis identified three co-circulating hepatitis A virus (HAV) strains of genotype IA: VRD_521_2016, V16-25801 and RIVM-HAV16-090. We categorised cases as confirmed, probable or possible, according to the EU outbreak case definitions. Confirmed cases were infected with one of the three outbreak strains. We investigated case characteristics and strain-specific risk factors for transmission. A total of 1,400 (34%) cases were confirmed; VRD_521_2016 and RIVM-HAV16-090 accounted for 92% of these. Among confirmed cases with available epidemiological data, 92% (361/393) were unvaccinated, 43% (83/195) travelled to Spain during the incubation period and 84% (565/676) identified as men who have sex with men (MSM). Results depict an HA outbreak of multiple HAV strains, within a cross-European population, that was particularly driven by transmission between non-immune MSM engaging in high-risk sexual behaviour. The most effective preventive measure to curb this outbreak is HAV vaccination of MSM, supplemented by primary prevention campaigns that target the MSM population and promote protective sexual behaviour.es_ES
dc.language.isoenges_ES
dc.publisherEuropean Centre for Disease Prevention and Control (ECDC) es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectHepatitis Aes_ES
dc.subjectHepatitis A viruses_ES
dc.subjectMen who have sex with men - MSMes_ES
dc.subjectSexually transmitted infectionses_ES
dc.subjectVaccine-preventable diseaseses_ES
dc.subjectVaccines and immunisationes_ES
dc.subject.meshDisease Outbreaks es_ES
dc.subject.meshAdolescent es_ES
dc.subject.meshAdult es_ES
dc.subject.meshAged es_ES
dc.subject.meshAged, 80 and over es_ES
dc.subject.meshChild es_ES
dc.subject.meshChild, Preschool es_ES
dc.subject.meshEurope es_ES
dc.subject.meshEuropean Union es_ES
dc.subject.meshGenotype es_ES
dc.subject.meshHepatitis A es_ES
dc.subject.meshHepatitis A virus es_ES
dc.subject.meshHomosexuality, Male es_ES
dc.subject.meshHospitalization es_ES
dc.subject.meshHumans es_ES
dc.subject.meshInfant es_ES
dc.subject.meshInfant, Newborn es_ES
dc.subject.meshMale es_ES
dc.subject.meshMiddle Aged es_ES
dc.subject.meshRisk Factors es_ES
dc.subject.meshSexual Behavior es_ES
dc.subject.meshSpain es_ES
dc.subject.meshYoung Adult es_ES
dc.titleHepatitis A outbreak disproportionately affecting men who have sex with men (MSM) in the European Union and European Economic Area, June 2016 to May 2017.es_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID30131095es_ES
dc.format.volume23es_ES
dc.format.number33es_ES
dc.identifier.doi10.2807/1560-7917.ES.2018.23.33.1700641es_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1560-7917
dc.relation.publisherversionhttp://dx.doi.org/10.2807/1560-7917.ES.2018.23.33.1700641es_ES
dc.identifier.journalEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletines_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES


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Atribución 4.0 Internacional
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