Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/11171
Absence of IgG antibodies among high-risk contacts of two confirmed cases of Crimean-Congo haemorrhagic fever in the autonomous region of Madrid (Spain).
Latasa, Pello | De Ory, Fernando de ISCIII | Arribas, José Ramón | Sánchez-Uriz, Maria Ángeles | Sanchez-Arcilla, Igmacio | Ordobas, Maria | Negredo, Anabel ISCIII | Trigo, Elena | Delgado, Pilar CNIC | Marzola, Marco | Lopaz, Maria Ángeles | Sanchez-Seco, Paz ISCIII | Calle-Prieto, Fernando de la | Ferrera, Pilar | Rodriguez, Elena CNIC | Martin, Alejandro | Del Cerro, Maria Felipa | Córdoba, Esther | Mora-Rillo, Marta | Esteban, Maria José
J Infect Public Health. 2020 Oct;13(10):1595-1598.
Crimean-Congo haemorrhagic fever (CCHF) is a widely distributed tick-borne disease. In Spain, the disease has emerged as outbreak associated with high-risk exposures. Our goal was to evaluate the prevalence of antibodies against the CCHF virus (CCHFV) in high-risk contacts. A cross-sectional study was conducted. Three hundred eighty-six high-risk contacts were identified comprising family contacts and hospital workers who had attended the cases. Fifty-seven cases with closer exposure were selected. However, forty-nine cases participated in the study. IgG antibodies were detected by immunoenzymatic techniques. All determinations tested negative for anti-CCHFV IgG antibodies. Most of the responders were women (73.5%), and belong to the intensive care department (53.1%). In relation to other possible sources of exposures, 18.4% travelled to countries with CCHF transmission risk. No CCHF positivity was recorded among selected high-risk contacts. This highlights the importance of standard precautions which might have protected healthcare workers and care providers from CCHF infection.
Crimean-Congo haemorrhagic fever virus | Health surveillance | Infectious disease transmission | Serology
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