Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/10293
Comparison of imported Plasmodium ovale curtisi and P. ovale wallikeri infections among patients in Spain, 2005-2011.
Rojo-Marcos, Gerardo | Ramírez-Olivencia, German ISCIII | García-Bujalance, Silvia | Elcuaz-Romano, Rosa | Díaz-Menéndez, Marta | Calderón, María | García-Bermejo, Isabel | Ruiz-Giardin, José Manuel | Merino-Fernández, Francisco Jesús | Torrús-Tendero, Diego | Delgado-Iribarren, Alberto | Ribell-Bachs, Mónica | Arévalo-Serrano, Juan | Cuadros-González, Juan | Rubio Muñoz, Jose Miguel ISCIII
Emerg Infect Dis . 2014 Mar;20(3):409-16.
Sequencing data from Plasmodium ovale genotypes co-circulating in multiple countries support the hypothesis that P. ovale curtisi and P. ovale wallikeri are 2 separate species. We conducted a multicenter, retrospective, comparative study in Spain of 21 patients who had imported P. ovale curtisi infections and 14 who had imported P. ovale wallikeri infections confirmed by PCR and gene sequencing during June 2005-December 2011. The only significant finding was more severe thrombocytopenia among patients with P. ovale wallikeri infection than among those with P. ovale curtisi infection (p = 0.031). However, we also found nonsignificant trends showing that patients with P. ovale wallikeri infection had shorter time from arrival in Spain to onset of symptoms, lower level of albumin, higher median maximum core temperature, and more markers of hemolysis than did those with P. ovale curtisi infection. Larger, prospective studies are needed to confirm these findings.
Adolescent | Adult | Child | Comorbidity | Female | History, 21st Century | Humans | Malaria | Male | Middle Aged | Plasmodium ovale | Retrospective Studies | Spain | Thrombocytopenia | Young Adult
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