PURPOSE This study has been focused on assessing the Open Science scenario of cancer research during the period 2011-2021, in terms of the derived scientific publications and raw data dissemination. METHODS A cancer search equation was executed in the Science Citation Index-Expanded, collecting ...

OBJECTIVES The aim of the study was to characterize the circulating immunome of patients with EoE before and after proton pump inhibitor (PPI) treatment in order to identify potential non-invasive biomarkers of treatment response. METHODS PBMCs from 19 healthy controls and 24 EoE patients were s...

Objectives: To analyse the impact of the most clinically relevant β-lactamases and their interplay with low outer membrane permeability on the activity of cefiderocol, ceftazidime/avibactam, aztreonam/avibactam, cefepime/enmetazobactam, cefepime/taniborbactam, cefepime/zidebactam, imipenem/relebact...

Visceral leishmaniasis is a deadly infectious disease and is one of the world's major neglected health problems. Because the symptoms of infection are similar to other endemic diseases, accurate diagnosis is crucial for appropriate treatment. Definitive diagnosis using splenic or bone marrow aspira...

Glial fibrillary acidic protein (GFAP), a proxy of astrocyte reactivity, has been proposed as biomarker of Alzheimer's disease. However, there is limited information about the correlation between blood biomarkers and post-mortem neuropathology. In a single-centre prospective clinicopathological coh...

Social media (SoMe) has witnessed remarkable growth and emerged as a dominant method of communication worldwide. Platforms such as Facebook, X (formerly Twitter), LinkedIn, Instagram, TikTok, and YouTube have become important tools of the digital native generation. In the field of medicine, particu...

El invierno de 2022-23, ha tenido un carácter cálido en la mayoría de la península, considerado por la Agencia Estatal de Meteorología (AEMET) el décimo invierno más cálido desde el comienzo de la serie en 1961 y el quinto más cálido del siglo XXI. Sin embargo, hubo diversos episodios fríos con tem...

BACKGROUND Allergic diseases begin early in life and are often chronic, thus creating an inflammatory environment that may precede or exacerbate other pathologies. In this regard, allergy has been associated to metabolic disorders and with a higher risk of cardiovascular disease, but the underlyin...

En las últimas décadas, el aumento de los casos de enfermedades tropicales transmitidas por vectores, como el dengue, la malaria y el chikungunya, han elevado la preocupación por que este tipo de patologías se extiendan por Europa. Los factores climáticos afectan directamente a la expansión y distr...

Systemic AL amyloidosis is a challenging disease for which many patients are considered frail in daily clinical practice. However, no study has so far addressed frailty and its impact on the outcome of these patients. We built a simple score to predict mortality based on three frailty-associated va...

Cardiovascular disease is the leading cause of death worldwide with myocardial infarction being the most prevalent. Currently, no cure is available to either prevent or revert the massive death of cardiomyocytes that occurs after a myocardial infarction. Adult mammalian hearts display a limited reg...

La Comisión Interministerial de Biomonitorización Humana (CIBMH) emana del Plan Estratégico de Salud y Medio Ambiente (PESMA), como una herramienta para la implementación de la biomonitorización humana (BMH) a nivel nacional, asegurando su integración con las estrategias europeas. La BMH tiene como...