Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/7657
Título
Synthesis, transport and incorporation into the nuclear envelope of A-type lamins and inner nuclear membrane proteins
Autor(es)
Gonzalez, Jose M CNIC | Andres, Vicente CNIC
Fecha de publicación
2011-12
Cita
Biochem Soc Trans. 2011; 39(6):1758-63
Idioma
Inglés
Tipo de documento
journal article
Resumen
The mammalian NE (nuclear envelope), which separates the nucleus from the cytoplasm, is a complex structure composed of nuclear pore complexes, the outer and inner nuclear membranes, the perinuclear space and the nuclear lamina (A- and B-type lamins). The NE is completely disassembled and reassembled at each cell division. In the present paper, we review recent advances in the understanding of the mechanisms implicated in the transport of inner nuclear membrane and nuclear lamina proteins from the endoplasmic reticulum to the nucleus in interphase cells and mitosis, with special attention to A-type lamins.
MESH
Animals | Humans | Lamin Type A | Membrane Proteins | Mitosis | Nuclear Envelope | Nuclear Proteins | Protein Transport
Versión en línea
DOI
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