dc.contributor.author | Camafeita, Emilio | |
dc.contributor.author | Lamas, José Ramón | |
dc.contributor.author | Calvo, Enrique | |
dc.contributor.author | Tornero-Esteban, Pilar | |
dc.contributor.author | Lopez, Juan Antonio | |
dc.contributor.author | Fernandez-Gutierrez, Benjamin | |
dc.date.accessioned | 2019-04-29T12:33:40Z | |
dc.date.available | 2019-04-29T12:33:40Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | Clin Proteomics. 2014; 11(1):33 | es_ES |
dc.identifier.issn | 1542-6416 | es_ES |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/7533 | |
dc.description.abstract | Osteoarthritis (OA) is considered the most prevalent form of arthritis. The aim of this study was to verify potential protein OA biomarkers by applying Selected Reaction Monitoring (SRM) assays to protein extracts obtained from Bone Marrow-Mesenchymal Stem Cells (BM-MSCs) isolated from OA patients. BM aspirates were obtained from the femoral channel of OA patients at the time of surgery and from the femoral channel of hip fracture subjects without OA during hip joint replacement surgery for the treatment of subcapital fracture. SRM results verified the differential expression of several protein biomarkers in BM-MSCs from OA patients. | es_ES |
dc.description.sponsorship | CNIC is supported by the Ministerio de Economía y Competitividad and the Fundación Pro CNIC. Support was also provided by FIS PI10/00178 and RETICS Program, RD08/0075 (RIER) from Instituto de Salud Carlos III (ISCIII). JRL is a recipient of Miguel Servet Program from Instituto de Salud Carlos III (ISCIII). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | BioMed Central (BMC) | es_ES |
dc.type.hasVersion | VoR | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Mesenchymal stem cells | es_ES |
dc.subject | Osteoarthritis | es_ES |
dc.subject | Selected reaction monitoring | es_ES |
dc.title | Selected reaction monitoring assays in mesenchymal stem cells from osteoarthritis patients | es_ES |
dc.type | journal article | es_ES |
dc.rights.license | Atribución 4.0 Internacional | * |
dc.identifier.pubmedID | 25249828 | es_ES |
dc.format.volume | 11 | es_ES |
dc.format.number | 1 | es_ES |
dc.format.page | 33 | es_ES |
dc.identifier.doi | 10.1186/1559-0275-11-33 | es_ES |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | |
dc.contributor.funder | Instituto de Salud Carlos III | |
dc.contributor.funder | Fundación ProCNIC | |
dc.description.peerreviewed | Sí | es_ES |
dc.identifier.journal | Clinical proteomics | es_ES |
dc.repisalud.orgCNIC | CNIC::Unidades técnicas::Proteómica / Metabolómica | es_ES |
dc.repisalud.institucion | CNIC | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/RD08/0075 | es_ES |
dc.rights.accessRights | open access | es_ES |