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dc.contributor.authorFernandez-Jimenez, Rodrigo 
dc.contributor.authorJaslow, Risa
dc.contributor.authorBansilal, Sameer
dc.contributor.authorSantana, Maribel
dc.contributor.authorDiaz-Munoz, Raquel
dc.contributor.authorLatina, Jacqueline
dc.contributor.authorSoto, Ana V
dc.contributor.authorVedanthan, Rajesh
dc.contributor.authorAl-Kazaz, Mohamed
dc.contributor.authorGiannarelli, Chiara
dc.contributor.authorKovacic, Jason C
dc.contributor.authorBagiella, Emilia
dc.contributor.authorKasarskis, Andrew
dc.contributor.authorFayad, Zahi A
dc.contributor.authorHajjar, Roger J
dc.contributor.authorFuster, Valentin
dc.identifier.citationJ Am Coll Cardiol. 2019; 73(16):2011-2021es_ES
dc.description.abstractBACKGROUND: Preschool-based interventions offer promise to instill healthy behaviors in children, which can be a strategy to reduce the burden of cardiovascular disease later. However, their efficacy in underserved communities is not well established. OBJECTIVES: The purpose of this study was to assess the impact of a preschool-based health promotion educational intervention in an underserved community. METHODS: This cluster-randomized controlled study involved 15 Head Start preschools in Harlem, New York. Schools and their children were randomized 3:2 to receive either a 4-month (50 h) educational intervention to instill healthy behaviors in relation to diet, physical activity, body/heart awareness, and emotion management; or their standard curriculum (control). The primary outcome was the change from baseline in the overall knowledge, attitudes, and habits (KAH) score of the children at 5 months. As secondary outcomes, we evaluated the changes in KAH subcomponents and emotion comprehension. Linear mixed-effects models were used to test for intervention effects. RESULTS: The authors enrolled 562 preschool children age 3 to 5 years, 51% female, 54% Hispanic/Latino, and 37% African-American. Compared with the control group, the mean relative change from baseline in the overall KAH score was ∼2.2 fold higher in the intervention group (average absolute difference of 2.86 points; 95% confidence interval: 0.58 to 5.14; p = 0.014). The maximal effect was observed in children who received >75% of the curriculum. Physical activity and body/heart awareness components, and knowledge and attitudes domains, were the main drivers of the effect (p values <0.05). Changes in emotion comprehension trended toward favoring intervened children. CONCLUSIONS: This multidimensional school-based educational intervention may be an effective strategy for establishing healthy behaviors among preschoolers from a diverse and socioeconomically disadvantaged community. Early primordial prevention strategies may contribute to reducing the global burden of cardiovascular disease. (Family-Based Approach in a Minority Community Integrating Systems-Biology for Promotion of Health [FAMILIA]; NCT02343341).es_ES
dc.description.sponsorshipThis study is funded by the American Heart Association under grant No. 14SFRN20490315. The CNIC is supported by the Ministerio de Ciencia, Innovación y Universidades and the Pro CNIC Foundation, and is a Severo Ochoa Center of Excellence (SEV-2015-0505). Dr. Fernandez-Jimenez is a recipient of funding from the European Union Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 707642. Dr. Bansilal is an employee of Bayer Pharmaceuticals.es_ES
dc.relation.isversionofPublisher's versiones_ES
dc.subjecthealth promotiones_ES
dc.subjectvulnerable populationses_ES
dc.titleChild Health Promotion in Underserved Communities: The FAMILIA Triales_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.contributor.funderAmerican Heart Associationes_ES
dc.contributor.funderMinisterio de Ciencia, Innovación y Universidades (España)es_ES
dc.contributor.funderFundación ProCNICes_ES
dc.contributor.funderEuropean Commissiones_ES
dc.contributor.funderBayer Healthcare Pharmaceuticals-Bayer Pharma AGes_ES
dc.identifier.journalJournal of the American College of Cardiologyes_ES
dc.repisalud.orgCNICCNIC::Grupos de investigación::Imagen Cardiovascular y Estudios Poblacionaleses_ES
dc.repisalud.orgCNICCNIC::Grupos de investigación::Laboratorio Traslacional para la Imagen y Terapia Cardiovasculares_ES

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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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