dc.contributor.author | Laveriano-Santos, Emily P | |
dc.contributor.author | Arancibia-Riveros, Camila | |
dc.contributor.author | Parilli-Moser, Isabella | |
dc.contributor.author | Ramírez-Garza, Sonia L | |
dc.contributor.author | Tresserra-Rimbau, Anna | |
dc.contributor.author | Ruiz-León, Ana María | |
dc.contributor.author | Estruch, Ramón | |
dc.contributor.author | Bodega, Patricia | |
dc.contributor.author | de Miguel, Mercedes | |
dc.contributor.author | de Cos-Gandoy, Amaya | |
dc.contributor.author | Carral, Vanesa | |
dc.contributor.author | Santos-Beneit, Gloria | |
dc.contributor.author | Fernández-Alvira, Juan M | |
dc.contributor.author | Fernández-Jiménez, Rodrigo | |
dc.contributor.author | Lamuela-Raventós, Rosa M | |
dc.date.accessioned | 2023-03-17T12:52:50Z | |
dc.date.available | 2023-03-17T12:52:50Z | |
dc.date.issued | 2022-09-14 | |
dc.identifier.citation | Sci Rep. 2022 Sep 14;12(1):15468 | es_ES |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/15672 | |
dc.description.abstract | To study the relationship between urinary total polyphenol excretion (TPE) in adolescents and ideal cardiovascular (CVH) metrics. 1151 adolescents aged 12.04 (0.46) years participating in the SI! Program for Secondary Schools were selected based on the availability of urine samples and information required to assess CVH metrics. Data on health behaviours (smoking status, body mass index, physical activity, and healthy diet) and health factors (blood pressure, total cholesterol, and blood glucose) were used to calculate the CVH metrics. TPE in urine was analysed by a Folin-Ciocalteu method after solid-phase extraction. Associations between TPE (categorized into tertiles) and CVH metrics (total and separate scores) were assessed using multilevel mixed-effect regression models. Higher TPE levels were associated with higher (healthier) CVH scores and ideal smoking status (OR 1.54, 95% CI 1.10; 1.87, p value = 0.007), physical activity (OR 1.12, 95% CI 1.02; 1.23, p value = 0.022) and total cholesterol (OR 1.78, 95% CI 1.16; 2.73, p value = 0.009) after multivariate adjustment. An association between TPE and total CVH scores was observed only in boys. Girls with higher TPE had higher rates of ideal total cholesterol and blood pressure. According to our findings, higher urinary TPE is related to better CVH scores, with relevant differences in this association by gender. | es_ES |
dc.description.sponsorship | The authors wish to thank all the volunteers and their families, teachers, and schools for their contribution to the SI! Program for Secondary Schools. The SI! Program for Secondary Schools trial was supported by the SHE Foundation, the “la Caixa” Foundation (grant numbers LCF/PR/CE16//10700001 and LCF/PR/MS19/12220001), and the Fundació la Marató de TV3 (grant number 369/C/2016). Support was also provided by the Ministerio de Ciencia, Innovación y Universidades (grant number AGL2016–75329-R), and Generalitat de Catalunya. Rodrigo
Fernández-Jiménez is a recipient of grant PI19/01704 funded by the Fondo de Investigación Sanitaria- Instituto
de Salud Carlos III (ISCIII) and co-funded by the European Regional Development Fund/European Social Fund
"A way to make Europe"/"Investi
ng in your future". The Centro Nacional de Investigaciones Cardiovasculares is
supported by the ISCIII, the Ministerio de Ciencia e Innovación, and the Pro CNIC Foundation, and is a Severo
Ochoa Center of Excellence (CEX2020-001041-S). Anna Tresserra-Rimbau was supported by a Serra Húnter
Fellowship. Emily P. Laveriano-Santos is thankful for the FI-SDUR (EMC/3345/2020) fellowship from the Generalitat
de Catalunya. Isabella Parilli-Moser thanks the FI-SDUR (EMC/2703/2019) fellowship. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Nature Publishing Group | es_ES |
dc.type.hasVersion | VoR | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject.mesh | Cardiovascular Diseases | es_ES |
dc.subject.mesh | Polyphenols | es_ES |
dc.subject.mesh | Adolescent | es_ES |
dc.subject.mesh | Cholesterol | es_ES |
dc.subject.mesh | Cross-Sectional Studies | es_ES |
dc.subject.mesh | Female | es_ES |
dc.subject.mesh | Humans | es_ES |
dc.subject.mesh | Male | es_ES |
dc.subject.mesh | Quality Indicators, Health Care | es_ES |
dc.title | Total urinary polyphenols and ideal cardiovascular health metrics in Spanish adolescents enrolled in the SI Program: a cross-sectional study. | es_ES |
dc.type | journal article | es_ES |
dc.rights.license | Atribución 4.0 Internacional | * |
dc.identifier.pubmedID | 36104478 | es_ES |
dc.format.volume | 12 | es_ES |
dc.format.number | 1 | es_ES |
dc.format.page | 15468 | es_ES |
dc.identifier.doi | 10.1038/s41598-022-19684-6 | es_ES |
dc.contributor.funder | Fundación La Caixa | es_ES |
dc.contributor.funder | Fundación La Marató TV3 | es_ES |
dc.contributor.funder | Ministerio de Ciencia e Innovación (España) | es_ES |
dc.contributor.funder | Instituto de Salud Carlos III | es_ES |
dc.contributor.funder | Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF) | es_ES |
dc.contributor.funder | Fundación ProCNIC | es_ES |
dc.contributor.funder | Ministerio de Ciencia e Innovación. Centro de Excelencia Severo Ochoa (España) | es_ES |
dc.description.peerreviewed | Sí | es_ES |
dc.identifier.e-issn | 2045-2322 | es_ES |
dc.identifier.journal | Scientific reports | es_ES |
dc.repisalud.orgCNIC | CNIC::Grupos de investigación::Imagen Cardiovascular y Estudios Poblacionales | es_ES |
dc.repisalud.institucion | CNIC | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/369/C/2016 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/CEX2020-001041-S | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/EMC/2703/2019 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/EMC/3345/2020 | es_ES |