dc.contributor.author | Macias, Alvaro | |
dc.contributor.author | González-Guerra, Andrés | |
dc.contributor.author | Moreno-Manuel, Ana I. | |
dc.contributor.author | Cruz, Francisco M. | |
dc.contributor.author | Gutiérrez, Lilian K. | |
dc.contributor.author | García-Quintáns, Nieves | |
dc.contributor.author | Roche-Molina, Marta | |
dc.contributor.author | Bermúdez-Jiménez, Francisco | |
dc.contributor.author | Andres, Vicente | |
dc.contributor.author | Vera-Pedrosa, María Linarejos | |
dc.contributor.author | Martínez-Carrascoso, Isabel | |
dc.contributor.author | Bernal, Juan A. | |
dc.contributor.author | Jalife, Jose | |
dc.date.accessioned | 2022-12-07T13:55:49Z | |
dc.date.available | 2022-12-07T13:55:49Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Macías, Á., González-Guerra, A., Moreno-Manuel, A.I. et al. Kir2.1 dysfunction at the sarcolemma and the sarcoplasmic reticulum causes arrhythmias in a mouse model of Andersen–Tawil syndrome type 1. Nat Cardiovasc Res 1, 900–917 (2022). | es_ES |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/15257 | |
dc.description.sponsorship | We thank C. Galán-Arriola (from CNIC) for help in the graphical
illustration of the manuscript; M. Fernández-Tenorio (from the
University of Bern) for valuable guidance in the experimental details
of calcium dynamics in permeabilized cells; and H. Valdivia and
F. Alvarado (both from the University of Wisconsin-Madison) for
valuable comments and discussions regarding this manuscript.
The project leading to these results has received funding from “La
Caixa” Banking Foundation under the Project code HR18-00304 (LCF/
PR/HR19/52160013); SQTS Project (PI20/01220) of the public call
Proyectos de investigación en salud 2020 (PI-FIS-2020), funded by
Instituto de Salud Carlos III (ISCIII) and co-funded by the European
Union (FEDER/FSE), ‘Una manera de hacer Europa’/ “El FSE invierte
en tu futuro”; Genotype Specific Arrhythmogenic Mechanisms
in Andersen–Tawil syndrome (736/C/2020) of the call Ayudas a la
investigación en enfermedades raras 2020 (LAMARATO-2020)” amb
el suport de la Fundació La Marató de TV3; and the European Union’s
Horizon 2020 research and innovation programme under grant
agreement GA-965286 (funded by the European Union). The views
and opinions expressed are, however, those of the authors only and
do not necessarily reflect those of the European Union. Neither the
European Union nor the granting authority can be held responsible for
them. The Dynamic Microscopy and Imaging Unit - ICTS-ReDib grant
ICTS-2018-04-CNIC-16 funded by MCIN/AEI /10.13039/501100011033
and ERDF “A way of making Europe”; EQC2018-005070-P funded
by MCIN/AEI /10.13039/501100011033 and FEDER “Una manera
de hacer Europa”, to J.J.; Project PID2020-116935RB-I00 MCIN/
AEI/10.13039/501100011033, Fondo Europeo de Desarrollo
Regional FEDER Una manera de hacer Europa/Ministerio de Ciencia
e Innovación–Agencia Estatal de Investigación and MCIU grants
BFU2016-75144-R and PID2020-116935RB-I00 to J.A.B. and SAF2016-
79490-R to V.A. from the Ministerio de Ciencia e Innovación (MCIN),
with co-funding from the European Regional Development Fund (“A
way to build Europe”). A.I.M.M. holds an FPU contract (FPU20/01569),
Ministerio de Universidades; L.K.G. holds an FPI contract (PRE2018-
083530), Ministerio de Economía y Competitividad de España cofunded by Fondo Social Europeo “El Fondo Social Europeo invierte
en tu futuro”, attached to the Project SEV-2015-0505-18-2; M.L.V.P.
held contract PEJD-2019-PRE/BMD-15982, funded by Consejería de
Educación e Investigación de la Comunidad de Madrid y Fondo Social
Europeo “El FSE invierte en tu futuro”; and I.M.C. holds PFIS contract
(FI21/00243), funded by Instituto de Salud Carlos III and Fondo Social
Europeo Plus (FSE+), “Cofinanciado por la Unión Europea”. The CNIC is
supported by the Instituto de Salud Carlos III (ISCIII), MCIN and the Pro
CNIC Foundation and the Severo Ochoa Center of Excellence (grant
CEX2020-001041-S, funded by MICIN/AEI/10.13039/501100011033). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Springer | es_ES |
dc.type.hasVersion | VoR | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.title | Kir2.1 dysfunction at the sarcolemma and the sarcoplasmic reticulum causes arrhythmias in a mouse model of Andersen–Tawil syndrome type 1 | es_ES |
dc.type | journal article | es_ES |
dc.rights.license | Atribución 4.0 Internacional | * |
dc.format.volume | 1 | es_ES |
dc.format.number | 10 | es_ES |
dc.format.page | 900-917 | es_ES |
dc.identifier.doi | 10.1038/s44161-022-00145-2 | es_ES |
dc.contributor.funder | Fundación La Caixa | es_ES |
dc.contributor.funder | Instituto de Salud Carlos III | es_ES |
dc.contributor.funder | Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF) | es_ES |
dc.contributor.funder | Fundación La Marató TV3 | es_ES |
dc.contributor.funder | Unión Europea. Comisión Europea. H2020 | es_ES |
dc.contributor.funder | Ministerio de Ciencia e Innovación (España) | es_ES |
dc.contributor.funder | Agencia Estatal de Investigación (España) | es_ES |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | es_ES |
dc.contributor.funder | Comunidad de Madrid (España) | es_ES |
dc.contributor.funder | Fundación ProCNIC | es_ES |
dc.contributor.funder | Ministerio de Ciencia e Innovación. Centro de Excelencia Severo Ochoa (España) | es_ES |
dc.description.peerreviewed | Sí | es_ES |
dc.identifier.e-issn | 2731-0590 | es_ES |
dc.relation.publisherversion | 10.1038/s44161-022-00145-2 | es_ES |
dc.identifier.journal | Nature Cardiovascular Research | es_ES |
dc.repisalud.orgCNIC | CNIC::Grupos de investigación::Arritmias Cardíacas | es_ES |
dc.repisalud.institucion | CNIC | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/H2020/736/C/2020 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/H2020/GA-965286 | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/HR18-00304 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/HR19/52160013 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/PI20/01220 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/ICTS-ReDib grant ICTS-2018-04-CNIC-16 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/10.13039/501100011033 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/EQC2018-005070-P | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/PID2020-116935RB-I00 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/BFU2016-75144-R | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/SAF2016- 79490-R | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/FPU20/01569 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/RE2018- 083530 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/SEV-2015-0505-18-2 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/PEJD-2019-PRE/BMD-15982 | es_ES |
dc.relation.projectFECYT | info:eu-repo/grantAgreement/ES/CEX2020-001041-S | es_ES |