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dc.contributor.authorFernandez-Alvira, Juan Miguel 
dc.contributor.authorFernandez-Jimenez, Rodrigo 
dc.contributor.authorde Miguel, Mercedes 
dc.contributor.authorSantos-Beneit, Gloria 
dc.contributor.authorBodega, Patricia 
dc.contributor.authorHill, Christopher A
dc.contributor.authorCarral, Vanesa
dc.contributor.authorRodríguez, Carla
dc.contributor.authorCarvajal, Isabel
dc.contributor.authorOrrit, Xavier 
dc.contributor.authorde Cos-Gandoy, Amaya 
dc.contributor.authorDal Re, Marian
dc.contributor.authorRobledo, Teresa
dc.contributor.authorFuster, Valentin
dc.identifier.citationAm Heart J. 2021 Oct;240:81-88.es_ES
dc.description.abstractThe Fifty-Fifty trial demonstrated that a peer-group-based intervention was able to improve healthy behaviors in individuals with cardiovascular (CV) risk factors immediately post-intervention. To determine the long-term sustainability of a one-year peer-group-based intervention focused on CV health and behavior. A total of 543 adults aged 25 to 50 years with at least 1 CV risk factor were screened and recruited, received initial training through workshops, and were then randomized 1:1 to a peer-group-based intervention group (IG) or a self-management control group (CG) for 12 months. At a median of 52 months from baseline, 321 participants were re-assessed (~60% retention). The primary outcome was the mean change in a composite health score related to blood pressure, exercise, weight, alimentation, and tobacco use (Fuster-BEWAT score [FBS], range 0-15). Intervention effects were assessed using linear-mixed effects models. The mean age of retained participants was 48.0 years (SD: 5.4), and 73% were female. Consistent with previous results, the change of overall FBS was significantly greater in the IG than in the CG at 12-month follow-up (between-group difference, 0.60 points; 95% CI, 0.08-1.12; P = .025). Assessment of long-term sustainability (52-month follow-up) showed that there were no between-group differences in the mean overall FBS (IG mean score, 8.52; 95% CI, 7.97-9.07 vs CG mean score, 8.51; 95% CI, 7.93-9.10; P = .972) or in the change of overall FBS from screening (IG mean change, 0.64; 95% CI, 0.00-1.28; CG mean change, 0.46; 95% CI, -0.20-1.12; P = .497). A one-year peer-group-based intervention showed favorable results at immediate post-intervention but did not demonstrate significant differences between the IG and CG at 52 months. Combination of an initial training period (workshops) with the maintenance of peer-support groups or other re-intervention strategies may be required to achieve sustained effects on healthy behaviors. identifier NCT02367963. Registered (
dc.description.sponsorshipThis study was co-funded by the SHE Foundation -“la Caixa” Foundation (LCF/PR/CE16/10700001 and LCF/PR/MS19/12220001) and the Ministry of Health, Social Services and Equality. R.F-J is recipient of funding from the Instituto de Salud Carlos III-Fondo de Investigacion Sanitaria (PI19/01704) co-funded by the European Regional Development Fund/European Social Fund (“A way to make Europe”/“Investing in your future”). The CNIC is supported by the Instituto de Salud Carlos III (ISCIII), the Ministry of Science and Innovation, and the Pro CNIC Foundation and is a Severo Ochoa Center of Excellence (SEV-2015-0505).es_ES
dc.subject.meshHealth Behavior es_ES
dc.subject.meshHeart Disease Risk Factorses_ES
dc.subject.meshPeer Influence es_ES
dc.subject.meshSocial Support es_ES
dc.subject.meshAdult es_ES
dc.subject.meshCardiovascular Diseases es_ES
dc.subject.meshFemale es_ES
dc.subject.meshFollow-Up Studies es_ES
dc.subject.meshHumans es_ES
dc.subject.meshMale es_ES
dc.subject.meshMiddle Aged es_ES
dc.subject.meshSelf-Management es_ES
dc.titleThe challenge of sustainability: Long-term results from the Fifty-Fifty peer group-based intervention in cardiovascular risk factors.es_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución-CompartirIgual 4.0 Internacional*
dc.identifier.journalAmerican Heart Journales_ES
dc.repisalud.orgCNICCardiovascular Health and Imaging Laboratoryes_ES
dc.rights.accessRightsopen accesses_ES
dc.relation.projectFISinfo:fis/Instituto de Salud Carlos III/Programa Estatal de Generación de Conocimiento y Fortalecimiento del Sistema Español de I+D+I/Subprograma Estatal de Generación de Conocimiento/PI19 - Proyectos de investigacion en salud (AES 2019). Modalidad proyectos en salud. (2019)/PI19/01704es_ES

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