Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/15698
Current Understanding of the Neural Stem Cell Niches.
Cells. 2022 Sep 26;11(19):3002
Neural stem cells (NSCs) are self-renewing, multipotent cells which give rise to all components of the central nervous system (CNS) during embryogenesis, but also activate in response to injury and disease and maintain a certain level of neurogenic activity throughout adulthood. This activity takes place in specialized regions of the brain, the neurovascular niches, whose main role is to control the behaviour of the CNS. In adult mammals, two main "canonical" niches have been described: The subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) of the dentate gyrus. This review discusses our current understanding of the neural stem cells and their canonical niches, as well as their structure, behaviours, and role in neural disease.
Neural Stem Cells | Animals | Lateral Ventricles | Mammals | Multipotent Stem Cells | Neurogenesis | Stem Cell Niche
Files in this item
- Current Understanding of the ...