Por favor, use este identificador para citar o enlazar este Item:http://hdl.handle.net/20.500.12105/15698
Título
Current Understanding of the Neural Stem Cell Niches.
Autor(es)
Fecha de publicación
2022-09-26
Cita
Cells. 2022 Sep 26;11(19):3002
Idioma
Inglés
Tipo de documento
review
Resumen
Neural stem cells (NSCs) are self-renewing, multipotent cells which give rise to all components of the central nervous system (CNS) during embryogenesis, but also activate in response to injury and disease and maintain a certain level of neurogenic activity throughout adulthood. This activity takes place in specialized regions of the brain, the neurovascular niches, whose main role is to control the behaviour of the CNS. In adult mammals, two main "canonical" niches have been described: The subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) of the dentate gyrus. This review discusses our current understanding of the neural stem cells and their canonical niches, as well as their structure, behaviours, and role in neural disease.
MESH
Neural Stem Cells | Animals | Lateral Ventricles | Mammals | Multipotent Stem Cells | Neurogenesis | Stem Cell Niche
Versión en línea
DOI
Aparece en las colecciones
Ficheros en el ítem
![Acceso Abierto Acceso Abierto](/themes/Mirage2/images/openAccess.png)
- Nombre:
- Current Understanding of the ...
- Tamaño:
- 3.843Mb
- Formato:
- Descripción:
- Artículo