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Macromolecular crowding meets tissue engineering by self-assembly: a paradigm shift in regenerative medicine.

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dc.contributor.authorSatyam, Abhigyan
dc.contributor.authorKumar, Pramod
dc.contributor.authorFan, Xingliang
dc.contributor.authorGorelov, Alexander
dc.contributor.authorRochev, Yury
dc.contributor.authorJoshi, Lokesh
dc.contributor.authorPeinado, Héctor
dc.contributor.authorLyden, David
dc.contributor.authorThomas, Benjamin
dc.contributor.authorRodriguez, Brian
dc.contributor.authorRaghunath, Michael
dc.contributor.authorPandit, Abhay
dc.contributor.authorZeugolis, Dimitrios
dc.contributor.funderScience Foundation Ireland
dc.contributor.funderHealth Research Board (Irlanda)
dc.contributor.funderCollege of Engineering and Informatics, Postgraduate Scholarship Scheme, NUI Galwayes_ES
dc.date.accessioned2024-02-05T12:55:49Z
dc.date.available2024-02-05T12:55:49Z
dc.date.issued2014-05-21
dc.description.abstractMMC, the addition of inert polydispersed macromolecules in the culture media, effectively emulates the dense in vivo extracellular space, resulting in amplified deposition of ECM in vitro and subsequent production of cohesive, ECM-rich living substitutes.es_ES
dc.description.peerreviewedSíes_ES
dc.description.sponsorshipWe thank Dr Oliver Carroll for laboratory management; and Mr Maciek Doczyk (http://doczykdesign.com) for his support in the preparation of Figure 1 of this manuscript. This work is supported by Science Foundation Ireland, Research Frontiers Programme, Project Number: SFI-09-RFP-ENM2483 to D.Z.; Science Foundation Ireland, E.T.S. Walton Visitor Awards Programme, Project Number: 08/W.1/B2568 to M.R., A.P. and D.Z.; Health Research Board, Project Number: HRA_POR/2011/84 to D.Z.; and College of Engineering and Informatics, Postgraduate Scholarship Scheme, NUI Galway to P.K. and D.Z.es_ES
dc.format.number19es_ES
dc.format.page3024es_ES
dc.format.volume26es_ES
dc.identifier.citationAdv Mater. 2014 ;26(19):3024-34.es_ES
dc.identifier.doi10.1002/adma.201304428es_ES
dc.identifier.e-issn1521-4095es_ES
dc.identifier.journalAdvanced materials (Deerfield Beach, Fla.)es_ES
dc.identifier.pubmedID24505025es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/17472
dc.language.isoenges_ES
dc.publisherWiley
dc.repisalud.institucionCNIOes_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.meshRegenerative Medicinees_ES
dc.subject.meshTissue Engineeringes_ES
dc.subject.meshAcrylic Resinses_ES
dc.subject.meshCell Linees_ES
dc.subject.meshCollagenes_ES
dc.subject.meshDextran Sulfatees_ES
dc.subject.meshExtracellular Matrixes_ES
dc.subject.meshFibroblastses_ES
dc.subject.meshHumanses_ES
dc.subject.meshMacromolecular Substanceses_ES
dc.subject.meshMatrix Metalloproteinase 2es_ES
dc.titleMacromolecular crowding meets tissue engineering by self-assembly: a paradigm shift in regenerative medicine.es_ES
dc.typejournal articlees_ES
dc.type.hasVersionSMURes_ES
dspace.entity.typePublication
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relation.isFunderOfPublication6cc1f42c-2ccd-4213-bf00-e933a7d32ac5
relation.isFunderOfPublication.latestForDiscovery90c15883-5c89-4576-9d05-5eebfc41784b
relation.isPublisherOfPublicationd81e762a-95f7-4917-88a1-8004b3b8caa7
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