Publication:
Detection of cutaneous leishmaniasis in three communities of Oti Region, Ghana

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dc.contributor.authorAkuffo, Richard
dc.contributor.authorSanchez Herrero, Carmen
dc.contributor.authorChicharro, Carmen
dc.contributor.authorCarrillo, Eugenia
dc.contributor.authorAttram, Naiki
dc.contributor.authorMosore, Mba-Tihssommah
dc.contributor.authorYeboah, Clara
dc.contributor.authorKotey, Nana Konama
dc.contributor.authorBoakye, Daniel
dc.contributor.authorRuiz-Postigo, Jose-Antonio
dc.contributor.authorMoreno, Javier
dc.contributor.authorWilson, Michael
dc.contributor.authorSarfo, Bismark
dc.contributor.authorAnto, Francis
dc.contributor.funderUniversity of Ghana (Ghana)es_ES
dc.contributor.funderWorld Health Organization (WHO/OMS)es_ES
dc.date.accessioned2022-03-28T09:40:17Z
dc.date.available2022-03-28T09:40:17Z
dc.date.issued2021-05
dc.description.abstractBackground: leishmaniasis (CL) is the most common type of leishmaniasis, a neglected tropical disease caused by parasites of the genus Leishmania. In Ghana, some studies in the Volta region have detected Leishmania parasites among persons with skin ulcers. Methodology/Principal findings: Using a cross-sectional study design, the prevalence of CL in three communities of the Oti Region of Ghana was investigated. Demographic and epidemiological data were obtained by a structured interviewer administered questionnaire. A total of 426 (12.4%) out of 3,440 participants screened had at least one skin ulcer. Of 595 skin ulcers sampled and tested by PCR for Leishmania infection, 150 (25.2%) ulcers from 136 individuals tested positive, accounting for an overall CL prevalence of 31.9% among persons with skin ulcers. Individual community CL prevalence of 23.2%, 29.8%, and 36.8% was observed in Ashiabre, Keri, and Sibi Hilltop respectively among persons with skin ulcers. Conclusions/Significance: Confirmation of CL in the study area suggests an active cycle of transmission of Leishmania infection. The observation of skin ulcers which tested negative to Leishmania infection suggests a need to test for additional causes of skin ulcers such as Treponema pallidum pertenue and Mycobacterium ulcerans in the study area.es_ES
dc.description.peerreviewedSíes_ES
dc.description.sponsorshipThis project was funded by the post graduate training scheme fellowship in implementation science by the Special Programme for Research and Training in Tropical Diseases (WHO/TDR) at the School of Public Health, University of Ghana. https://publichealth.ug.edu.gh/. The grant was received by RA. The authors declare that the funder had no role in the study design, data collection, data analysis, data interpretation, and in writing the manuscript.es_ES
dc.format.number5es_ES
dc.format.pagee0009416es_ES
dc.format.volume15es_ES
dc.identifier.citationPLoS Negl Trop Dis. 2021 May 24;15(5):e0009416.es_ES
dc.identifier.doi10.1371/journal.pntd.0009416es_ES
dc.identifier.e-issn1935-2735es_ES
dc.identifier.journalPLoS Neglected Tropical Diseaseses_ES
dc.identifier.pubmedID34029326es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/13843
dc.language.isoenges_ES
dc.publisherPublic Library of Science (PLOS)es_ES
dc.relation.publisherversionhttps://doi.org/10.1371/journal.pntd.0009416es_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectCutaneous Leishmaniasises_ES
dc.subjectGhanaes_ES
dc.subjectLleishmaniasises_ES
dc.subjectTropical diseasees_ES
dc.subjectParasiteses_ES
dc.titleDetection of cutaneous leishmaniasis in three communities of Oti Region, Ghanaes_ES
dc.typejournal articlees_ES
dc.type.hasVersionVoRes_ES
dspace.entity.typePublication
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