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Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan.

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dc.contributor.authorMolina-de la Fuente, Irene
dc.contributor.authorBenito, María José Sagrado
dc.contributor.authorFlevaud, Laurence
dc.contributor.authorOusley, Janet
dc.contributor.authorPasquale, Harriet Akello
dc.contributor.authorJulla, Ahmed
dc.contributor.authorAbdi, Abdirashid M
dc.contributor.authorChol, Buai Tut
dc.contributor.authorAbubakr, Bakri
dc.contributor.authorBenito, Agustín
dc.contributor.authorCasademont, Cristian
dc.contributor.authorNanclares, Carolina
dc.contributor.authorBerzosa, Pedro
dc.date.accessioned2026-01-22T09:03:46Z
dc.date.available2026-01-22T09:03:46Z
dc.date.issued2023-01
dc.description.abstractPfhrp2 and pfhrp3 gene deletions threaten the use of Plasmodium falciparum malaria rapid diagnostic tests globally. In South Sudan, deletion frequencies were 15.6% for pfhrp2, 20.0% for pfhrp3, and 7.5% for double deletions. Deletions were approximately twice as prevalent in monoclonal infections than in polyclonal infections.
dc.description.peerreviewedSí
dc.format.number1
dc.format.page154-159
dc.format.volume29
dc.identifier.citationMolina-de la Fuente I, Benito MJS, Flevaud L, Ousley J, Pasquale HA, Julla A, Abdi AM, Chol BT, Abubakr B, Benito A, Casademont C, Nanclares C, Berzosa P. Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan. Emerg Infect Dis. 2023 Jan;29(1):154-159. doi: 10.3201/eid2901.220775. PMID: 36573593; PMCID: PMC9796199.
dc.identifier.doi10.3201/eid2901.220775
dc.identifier.journalEmerging Infectious Diseases
dc.identifier.pubmedID36573593
dc.identifier.urihttps://hdl.handle.net/20.500.12105/27171
dc.language.isoeng
dc.publisherCenters for Disease Control and Prevention (CDC)
dc.relation.publisherversionhttps://doi.org/10.3201/eid2901.220775
dc.repisalud.centroISCIII::Centro Nacional de Medicina Tropical (CNMT)
dc.repisalud.institucionISCIII
dc.rights.accessRightsopen access
dc.rights.licenseAttribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectPlasmodium falciparum
dc.subjectRDT
dc.subjectSouth Sudan
dc.subjectDiagnosis
dc.subjectHistidine-rich protein
dc.subjectMalaria
dc.subjectMolecular epidemiology
dc.subjectParasites
dc.subjectSurveillance
dc.subjectVector-borne infections
dc.titlePlasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan.
dc.typeresearch article
dc.type.hasVersionVoR
dspace.entity.typePublication
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relation.isAuthorOfPublicationd1a82f32-e7e2-471c-a59d-5cd408ac7228
relation.isAuthorOfPublication.latestForDiscovery5be6287b-9ace-4e1d-818a-02203833da86
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