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Plasma-Derived Extracellular Vesicles as Potential Biomarkers in Heart Transplant Patient with Chronic Chagas Disease

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dc.contributor.authorCortes-Serra, Nuria
dc.contributor.authorMendes, Maria Tays
dc.contributor.authorMazagatos, Clara
dc.contributor.authorSegui-Barber, Joan
dc.contributor.authorEllis, Cameron C
dc.contributor.authorBallart, Cristina
dc.contributor.authorGarcía-Álvarez, Ana
dc.contributor.authorGállego, Montserrat
dc.contributor.authorGascón, Joaquim
dc.contributor.authorAlmeida, Igor C
dc.contributor.authorPinazo, María Jesús
dc.contributor.authorFernandez-Becerra, Carmen
dc.contributor.funderMinisterio de Ciencia, Innovación y Universidades (España)
dc.contributor.funderFundación La Marató TV3
dc.contributor.funderFundación Mundo Sano
dc.contributor.funderUnión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
dc.contributor.funderRETICS-Investigación colaborativa en Enfermedades Tropicales (RICET-ISCIII) (España)
dc.contributor.funderRed Iberoamericana Nuevas Herramientas para el Diagnóstico y la Evaluación del Paciente con Enfermedad de Chagases_ES
dc.contributor.funderNIH - National Institute on Minority Health and Health Disparities (NIMHD) (Estados Unidos)
dc.contributor.funderGovernment of Catalonia (España)
dc.date.accessioned2022-09-02T11:09:45Z
dc.date.available2022-09-02T11:09:45Z
dc.date.issued2020-08
dc.description.abstractChagas disease is emerging in countries to which it is not endemic. Biomarkers for earlier therapeutic response assessment in patients with chronic Chagas disease are needed. We profiled plasma-derived extracellular vesicles from a heart transplant patient with chronic Chagas disease and showed the potential of this approach for discovering such biomarkers.es_ES
dc.description.peerreviewedSíes_ES
dc.description.sponsorshipBarcelona Institute for Global Health (ISGlobal) receives support from the Spanish Ministry of Science, Innovation and Universities through the Centro de Excelencia Severo Ochoa 2019–2023 Program (CEX2018-000806-S). ISGlobal and Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP) are members of the Centres de Recerca de Catalunya (CERCA Program), Generalitat de Catalunya. Work in the laboratory of C.F.B. is funded by Fundació La Marató de TV3 (reference 566/U/2018) and Fundación Mundo Sano. This project was co-financed by the European Union through the European Regional Development Fund with the support of Secretaria d’Universitats i Recerca del Departament d’Empresa i Coneixement de la Generalitat de Catalunya. N.C., M.G., J.G., and M.J.P. receive funds from the Redes temáticas de investigación cooperativa en salud (RETICS), Spanish Tropical Diseases Network “RD12/0018/0010” and from the Agencia de Gestió d’Ajuts Universitaris i de Recerca, Generalitat de Catalunya; grant “2017 SGR 00924.” M.G., C.B., J.G., M.J.P., and I.C.A. belong to the Ibero-American Nuevas Herramientas para el Diagnóstico y la Evaluación del Paciente con Enfermedad de Chagas network. I.C.A. is partially supported by grants no. 2G12MD007592 and 5U54MD007592 from the National Institute on Minority Health and Health Disparities of the US National Institutes of Health. We are grateful to the Biomolecule Analysis Core Facility at University of Texas at El Paso, Border Biomedical Research Center, funded by National Institute on Minority Health and Health Disparities grants 2G12MD007592 and 5U54MD007592. M.T.M. received a PhD fellowship from the Science Without Borders Program, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil.es_ES
dc.format.number8es_ES
dc.format.page1846-1851es_ES
dc.format.volume26es_ES
dc.identifier.citationEmerg Infect Dis. 2020 Aug;26(8):1846-1851.es_ES
dc.identifier.doi10.3201/eid2608.191042es_ES
dc.identifier.e-issn1080-6059es_ES
dc.identifier.journalEmerging Infectious Diseaseses_ES
dc.identifier.pubmedID32687028es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/14939
dc.language.isoenges_ES
dc.publisherCenters for Disease Control and Prevention (CDC)
dc.relation.projectFECYTinfo:eu-repo/grantAgreement/MINECO//RD12%2F0018%2F0010/ES/Enfermedades tropicales/es_ES
dc.relation.projectFECYTinfo:eu-repo/grantAgreement/ES/CEX2018-000806-Ses_ES
dc.relation.publisherversionhttps://doi.org/10.3201/eid2608.191042es_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAtribución-NoComercial-CompartirIgual 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectBoliviaes_ES
dc.subjectChagas diseasees_ES
dc.subjectPlasmaes_ES
dc.subjectSpaines_ES
dc.subjectTrypanosoma cruzies_ES
dc.subjectBiomarkerses_ES
dc.subjectExtracellular vesicleses_ES
dc.subjectHeart transplantationes_ES
dc.subjectParasiteses_ES
dc.subjectProteomic analysises_ES
dc.subjectTropical diseaseses_ES
dc.subject.meshChagas Diseasees_ES
dc.subject.meshExtracellular Vesicleses_ES
dc.subject.meshHeart Transplantationes_ES
dc.subject.meshTrypanosoma cruzies_ES
dc.subject.meshBiomarkerses_ES
dc.subject.meshHumanses_ES
dc.titlePlasma-Derived Extracellular Vesicles as Potential Biomarkers in Heart Transplant Patient with Chronic Chagas Diseasees_ES
dc.typeresearch articlees_ES
dc.type.hasVersionVoRes_ES
dspace.entity.typePublication
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