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Plasma-Derived Extracellular Vesicles as Potential Biomarkers in Heart Transplant Patient with Chronic Chagas Disease

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URI: http://hdl.handle.net/20.500.12105/14939
DOI: 10.3201/eid2608.191042

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2020-08

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Abstract

Chagas disease is emerging in countries to which it is not endemic. Biomarkers for earlier therapeutic response assessment in patients with chronic Chagas disease are needed. We profiled plasma-derived extracellular vesicles from a heart transplant patient with chronic Chagas disease and showed the potential of this approach for discovering such biomarkers.

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Bolivia Chagas disease Plasma Spain Trypanosoma cruzi Biomarkers Extracellular vesicles Heart transplantation Parasites Proteomic analysis Tropical diseases

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Chagas Disease Extracellular Vesicles Heart Transplantation Trypanosoma cruzi Biomarkers Humans

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Bibliographic citation

Emerg Infect Dis. 2020 Aug;26(8):1846-1851.

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Centro Nacional de Epidemiología (CNE)
IGTP - Instituto de Investigación en Ciencias de la Salud Germans Trias i Pujol (Cataluña)

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https://doi.org/10.3201/eid2608.191042

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research article