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An unexpected role for PD-L1 in front-rear polarization and directional migration.

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dc.contributor.authorSánchez-Álvarez, Miguel
dc.contributor.authordel Pozo, Miguel Angel
dc.date.accessioned2023-11-28T16:00:29Z
dc.date.available2023-11-28T16:00:29Z
dc.date.issued2022-05-02
dc.description.abstractProgrammed cell death-ligand 1 (PD-L1)-mediated T cell inhibition through PD-1 is a key checkpoint frequently exploited by tumors to evade immunity. In this issue, Wang et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202108083) reveal an unexpected role for PD-L1 in promoting tumor cell front-rear polarity and directionally persistent cell migration, independently of PD-1.es_ES
dc.description.peerreviewedSíes_ES
dc.format.number5es_ES
dc.format.volume221es_ES
dc.identifier.citationJ Cell Biol. 2022 May 2;221(5):e202203137.es_ES
dc.identifier.doi10.1083/jcb.202203137es_ES
dc.identifier.e-issn1540-8140es_ES
dc.identifier.journalThe Journal of cell biologyes_ES
dc.identifier.pubmedID35416931es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/16740
dc.language.isoenges_ES
dc.publisherRockefeller University Presses_ES
dc.relation.publisherversion10.1083/jcb.202203137es_ES
dc.repisalud.institucionCNICes_ES
dc.repisalud.orgCNICCNIC::Grupos de investigación::Mecanoadaptación y Biología de Caveolases_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.meshB7-H1 Antigenes_ES
dc.subject.meshNeoplasmses_ES
dc.subject.meshCell Movementes_ES
dc.subject.meshHumanses_ES
dc.subject.meshProgrammed Cell Death 1 Receptores_ES
dc.subject.meshT-Lymphocyteses_ES
dc.subject.meshTumor Escapees_ES
dc.titleAn unexpected role for PD-L1 in front-rear polarization and directional migration.es_ES
dc.typeeditoriales_ES
dc.type.hasVersionVoRes_ES
dspace.entity.typePublication
relation.isAuthorOfPublication614c40fd-8aab-4cdb-ba1a-2552eb2ff021
relation.isAuthorOfPublication.latestForDiscovery614c40fd-8aab-4cdb-ba1a-2552eb2ff021

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