Publication: Type 2 diabetes and cognitive impairment in an older population with overweight or obesity and metabolic syndrome: baseline cross-sectional analysis of the PREDIMED-plus study.
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Full text access: http://hdl.handle.net/10668/13146
Full text access: http://hdl.handle.net/20.500.13003/9064
Publication date
2018-10-31
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Nature Publishing Group
Abstract
This study cross-sectionally examines in the elderly population: (a) the association of type 2 diabetes with executive function (EF); (b) the effect of BMI on both type 2 diabetes and EF; (c) the association between glycaemia control and EF in type 2 diabetes. 6823 older individuals with overweight/obesity and metabolic syndrome participating in the PREDIMED-PLUS study, were assessed with a battery of cognitive tests and a medical interview. ANOVA showed a significantly worse performance on EF in type 2 diabetes vs. non-diabetic individuals. Two complementary models were displayed: (1) in the whole sample, the presence of type 2 diabetes, depressive symptoms and BMI had a direct negative effect on EF, while apnoea had an indirect negative effect; (2) in the diabetes subsample, higher illness duration was associated with worse performance in EF. Participants with type 2 diabetes and HbA1c
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IBIMA-Plataforma BIONAND - Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (Andalucía)
IDIBAPS - Instituto de Investigaciones Biomédicas August Pi i Sunyer (Cataluña)
IDIBELL - Instituto de Investigación Biomédica de Bellvitge (Cataluña)
IdisBa - Instituto de Investigación Sanitaria Illes Balears (Baleares)
IdiSNA - Instituto de Investigación Sanitaria de Navarra (Navarra)
IdISSC - Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (Madrid)
Load more IDIBAPS - Instituto de Investigaciones Biomédicas August Pi i Sunyer (Cataluña)
IDIBELL - Instituto de Investigación Biomédica de Bellvitge (Cataluña)
IdisBa - Instituto de Investigación Sanitaria Illes Balears (Baleares)
IdiSNA - Instituto de Investigación Sanitaria de Navarra (Navarra)
IdISSC - Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (Madrid)