Publication: An Inbred Ecosystem that Supports Medulloblastoma.
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Cell Press
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Abstract
In a recent issue of Cell, Yao et al. use a unique genetic strategy to study sonic hedgehog-medulloblastoma. Their results reveal a complex network in the tumor microenvironment involving the trans-differentiation of cancer cells into astrocytes to fuel tumor growth.
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Researchin the Brain Metastasis Group is supported by MINECO grants MINECO-Retos SAF2017-89643-R (M.V.), Bristol-Myers Squibb-Melanoma Research Alliance Young Investigator Award 2017 (498103) (M.V.), Fundacion Ramon Areces (CIVP19S8163) (M.V.), Worldwide Cancer Research (19-0177) (M.V.), H2020-FETOPEN (828972) (M.V.), Clinic and Laboratory Integration Program CRI Award 2018 (54545) (M.V.), AECC Coordinated Translational Groups 2017 (GCTRA16015SEOA) (M.V.), LAB AECC 2019 (LABAE19002VALI) (M.V.), and La Caixa INPhINIT Fellowship (LCF/BQ/DI19/11730044) (A.d.P.-A.). M.V.is a Ramon y Cajal Investigator (RYC-2013-13365) and EMBO YIP (4053).
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Immunity . 2020 Mar 17;52(3):431-433.