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Deep Sequencing Reveals Occult Mansonellosis Coinfections in Residents From the Brazilian Amazon Village of São Gabriel da Cachoeira

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dc.contributor.authorCrainey, James Lee
dc.contributor.authorAguiar Costa, Carlos Henrique
dc.contributor.authorFerreira de Oliveira Leles, Lorena
dc.contributor.authorRibeiro da Silva, Túllio Romão
dc.contributor.authorde Aquino Narzetti, Luiz Henrique
dc.contributor.authorVinícius Serra Dos Santos, Yago
dc.contributor.authorCosta Conteville, Liliane
dc.contributor.authorCosta Pessoa, Felipe Arley
dc.contributor.authorCarvajal Cortés, José Joaquin
dc.contributor.authorPaulo Vicente, Ana Carolina
dc.contributor.authorRubio Muñoz, Jose Miguel
dc.contributor.authorBessa Luz, Sérgio Luiz
dc.contributor.funderFundação de Amparo à Pesquisa do Estado do Amazonas (Brasil)
dc.contributor.funderNational Council for Scientific and Technological Development (Brasil)
dc.date.accessioned2025-01-27T19:56:03Z
dc.date.available2025-01-27T19:56:03Z
dc.date.issued2020-11-05
dc.description.abstractMansonella ozzardi and Mansonella perstans infections both cause mansonellosis but are usually treated differently. Using a real-time polymerase chain reaction assay and deep sequencing, we reveal the presence of mansonellosis coinfections that were undetectable by standard diagnostic methods. Our results confirm mansonellosis coinfections and have important implications for the disease's treatment and diagnosis.
dc.description.peerreviewedSí
dc.description.sponsorshipThis work was supported by the Fundação de Amparo à Pesquisa do Estado do Amazonas (grant numbers 062.00647/2014, 062.01282/2018, and 002.00200/2019). A. C. P. V. and F. A. C. P. received fellowships from the Brazilian National Council for Scientific and Technological Development (CNPQ)
dc.format.number8
dc.format.page1990-1993
dc.format.volume71
dc.identifier.citationCrainey JL, Costa CHA, de Oliveira Leles LF, Ribeiro da Silva TR, de Aquino Narzetti LH, Serra Dos Santos YV, Costa Conteville L, Costa Pessoa FA, Carvajal Cortés JJ, Vicente ACP, Rubio Muñoz JM, Bessa Luz SL. Deep Sequencing Reveals Occult Mansonellosis Coinfections in Residents From the Brazilian Amazon Village of São Gabriel da Cachoeira. Clin Infect Dis. 2020 Nov 5;71(8):1990-1993.
dc.identifier.doi10.1093/cid/ciaa082
dc.identifier.e-issn1537-6591
dc.identifier.issn1058-4838
dc.identifier.journalClinical infectious diseases: an official publication of the Infectious Diseases Society of America
dc.identifier.pubmedID31995172
dc.identifier.urihttps://hdl.handle.net/20.500.12105/26157
dc.language.isoeng
dc.publisherOxford University Press
dc.relation.publisherversionhttps://doi.org/10.1093/cid/ciaa082
dc.repisalud.centroISCIII::Centro Nacional de Microbiología (CNM)
dc.repisalud.institucionISCIII
dc.rights.accessRightsopen access
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectMansonella ozzardi
dc.subjectMansonella perstans
dc.subjectBrazil
dc.subjectCoinfections
dc.subjectMansonellosis
dc.subject.meshAnimals
dc.subject.meshBrazil
dc.subject.meshCoinfection
dc.subject.meshHigh-Throughput Nucleotide Sequencing
dc.subject.meshHumans
dc.subject.meshMansonella
dc.subject.meshMansonelliasis
dc.titleDeep Sequencing Reveals Occult Mansonellosis Coinfections in Residents From the Brazilian Amazon Village of São Gabriel da Cachoeira
dc.typeresearch article
dc.type.hasVersionSMUR
dspace.entity.typePublication
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