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A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo

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URI: http://hdl.handle.net/20.500.12105/16073
DOI: 10.1038/s41467-021-27610-z

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2022-01-13

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Animals Antibodies, Bispecific Antibodies, Neutralizing Antibodies, Viral COVID-19 Chlorocebus aethiops Cryoelectron Microscopy HEK293 Cells Humans Mice, Transgenic Neutralization Tests Protein Binding Protein Conformation Protein Multimerization SARS-CoV-2 Single-Domain Antibodies Spike Glycoprotein, Coronavirus Vero Cells

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Nat Commun. 2022;13(1):155.

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https://doi.org/10.1038/s41467-021-27610-z.

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journal article