Sequence Analysis for Covid-19

Abstract

• Interaction of the virus and the host is very important • Virus needs to be handled in BSL2 laboratories • Host can present many predisposing low-risk contributing genetic factors – polygenic risk scores • Host can have rare variants that confer high risk – rare disease • Sequencing of the virus and host is possible • Data sharing accelerates discoveries • This can provide insight into the potential outcomes and guide treatment decisions