Browsing by Author "De la Torre, Rafael"
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Publication Type 2 diabetes and cognitive impairment in an older population with overweight or obesity and metabolic syndrome: baseline cross-sectional analysis of the PREDIMED-plus study.(Nature Publishing Group, 2018-10-31) Mallorquí-Bagué, Núria; Lozano-Madrid, María; Toledo, Estefanía; Corella, Dolores; Salas-Salvadó, Jordi; Cuenca-Royo, Aida; Vioque, Jesús; Romaguera, Dora; Martínez, J Alfredo; Wärnberg, Julia; López-Miranda, José; Estruch, Ramón; Bueno-Cavanillas, Aurora; Alonso-Gómez, Ángel; Tur, Josep A; Tinahones, Francisco J; Serra-Majem, Lluís; Martín, Vicente; Lapetra, José; Vázquez, Clotilde; Pintó, Xavier; Vidal, Josep; Daimiel, Lidia; Gaforio, José J; Matía, Pilar; Ros, Emilio; Granero, Roser; Buil-Cosiales, Pilar; Barragán, Rocío; Bulló, Mònica; Castañer, Olga; García-de-la-Hera, Manoli; Yáñez, Aina M; Abete, Itziar; García-Ríos, Antonio; Ruiz-Canela, Miguel; Díaz-López, Andrés; Jiménez-Murcia, Susana; Martínez-González, Miguel A; De la Torre, Rafael; Fernández-Aranda, FernandoThis study cross-sectionally examines in the elderly population: (a) the association of type 2 diabetes with executive function (EF); (b) the effect of BMI on both type 2 diabetes and EF; (c) the association between glycaemia control and EF in type 2 diabetes. 6823 older individuals with overweight/obesity and metabolic syndrome participating in the PREDIMED-PLUS study, were assessed with a battery of cognitive tests and a medical interview. ANOVA showed a significantly worse performance on EF in type 2 diabetes vs. non-diabetic individuals. Two complementary models were displayed: (1) in the whole sample, the presence of type 2 diabetes, depressive symptoms and BMI had a direct negative effect on EF, while apnoea had an indirect negative effect; (2) in the diabetes subsample, higher illness duration was associated with worse performance in EF. Participants with type 2 diabetes and HbA1c