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A synthetic lethal interaction between APC/C and topoisomerase poisons uncovered by proteomic screens.
Activation of the endomitotic spindle assembly checkpoint and thrombocytopenia in Plk1-deficient mice.
An Abl-FBP17 mechanosensing system couples local plasma membrane curvature and stress fiber remodeling during mechanoadaptation
An E2F7-dependent transcriptional program modulates DNA damage repair and genomic stability
Brain metastasis models: What should we aim to achieve better treatments? [preprint]
Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP
Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis.
Characterization of Novel Molecular Mechanisms Favoring Rac1 Membrane Translocation
Dynamics of telomeric repeat-containing RNA expression in early embryonic cleavage stages with regards to maternal age
ECM deposition is driven by caveolin-1-dependent regulation of exosomal biogenesis and cargo sorting.
Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice.
Interplay between hepatic mitochondria-associated membranes, lipid metabolism and caveolin-1 in mice
ITGB1-dependent upregulation of Caveolin-1 switches TGF beta signalling from tumour-suppressive to oncogenic in prostate cancer
Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells
Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation
Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense.
Mice with hyper-long telomeres show less metabolic aging and longer lifespans
Modulation of telomere protection by the PI3K/AKT pathway
Number and brightness analysis reveals that NCAM and FGF2 elicit different assembly and dynamics of FGFR1 in live cells