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Circadian Biology and Stroke.

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dc.contributor.authorLo, Eng H
dc.contributor.authorAlbers, Gregory W
dc.contributor.authorDichgans, Martin
dc.contributor.authorDonnan, Geoffrey
dc.contributor.authorEsposito, Elga
dc.contributor.authorFoster, Russell
dc.contributor.authorHowells, David W
dc.contributor.authorHuang, Yi-Ge
dc.contributor.authorJi, Xunming
dc.contributor.authorKlerman, Elizabeth B
dc.contributor.authorLee, Sarah
dc.contributor.authorLi, Wenlu
dc.contributor.authorLiebeskind, David S
dc.contributor.authorLizasoain, Ignacio
dc.contributor.authorMandeville, Emiri T
dc.contributor.authorMoro, Maria A
dc.contributor.authorNing, MingMing
dc.contributor.authorRay, David
dc.contributor.authorSakadžić, Sava
dc.contributor.authorSaver, Jeffrey L
dc.contributor.authorScheer, Frank A J L
dc.contributor.authorSelim, Magdy
dc.contributor.authorTiedt, Steffen
dc.contributor.authorZhang, Fang
dc.contributor.authorBuchan, Alastair M
dc.contributor.funderInstituto de Salud Carlos IIIes_ES
dc.contributor.funderNational Institutes of Health (Estados Unidos)es_ES
dc.contributor.funderWellcome Trustes_ES
dc.contributor.funderFondation Leducqes_ES
dc.contributor.funderUnión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)es_ES
dc.contributor.funderMinisterio de Ciencia e Innovación (España)es_ES
dc.contributor.funderFundación La Caixaes_ES
dc.date.accessioned2024-02-19T11:43:51Z
dc.date.available2024-02-19T11:43:51Z
dc.date.issued2021-06
dc.description.abstractCircadian biology modulates almost all aspects of mammalian physiology, disease, and response to therapies. Emerging data suggest that circadian biology may significantly affect the mechanisms of susceptibility, injury, recovery, and the response to therapy in stroke. In this review/perspective, we survey the accumulating literature and attempt to connect molecular, cellular, and physiological pathways in circadian biology to clinical consequences in stroke. Accounting for the complex and multifactorial effects of circadian rhythm may improve translational opportunities for stroke diagnostics and therapeutics.es_ES
dc.description.peerreviewedSíes_ES
dc.description.sponsorshipThis work was supported in part by the Wellcome Trust, the National Institutes of Health, and grants from Instituto de Salud Carlos III and cofinanced by the European Development Regional Fund “A way to achieve Europe” (PI20/00535 and RETICS RD16/0019/0009 to Dr Lizasoain) and from Spanish Ministry of Science and Innovation PID2019-106581RB-100, Leducq Foundation for Cardiovascular Research TNE-19CVD01, Fundación La Caixa HR17-00527 to Dr Moro; DWR MRC programme grant MR/P023576/1 and Wellcome Trust (107849/Z/15/Z) to Dr Ray.es_ES
dc.format.number6es_ES
dc.format.page2180es_ES
dc.format.volume52es_ES
dc.identifier.citationStroke. 2021 Jun;52(6):2180-2190.es_ES
dc.identifier.doi10.1161/STROKEAHA.120.031742es_ES
dc.identifier.e-issn1524-4628es_ES
dc.identifier.journalStrokees_ES
dc.identifier.pubmedID33940951es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/18221
dc.language.isoenges_ES
dc.publisherLippincott Williams & Wilkins (LWW)es_ES
dc.relation.projectFECYTinfo:eu-repo/grantAgreement/ES/PI20/00535es_ES
dc.relation.projectFECYTinfo:eu-repo/grantAgreement/ES/RD16/0019/0009es_ES
dc.relation.projectFECYTinfo:eu-repo/grantAgreement/ES/PID2019-106581RB-100es_ES
dc.relation.projectFECYTinfo:eu-repo/grantAgreement/ES/HR17-00527es_ES
dc.relation.publisherversion10.1161/STROKEAHA.120.031742es_ES
dc.repisalud.institucionCNICes_ES
dc.repisalud.orgCNICCNIC::Grupos de investigación::Fisiopatología Neurovasculares_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.meshAnimalses_ES
dc.subject.meshCircadian Rhythmes_ES
dc.subject.meshClinical Trials as Topices_ES
dc.subject.meshHumanses_ES
dc.subject.meshInflammation Mediatorses_ES
dc.subject.meshNeurovascular Couplinges_ES
dc.subject.meshStrokees_ES
dc.titleCircadian Biology and Stroke.es_ES
dc.typereview articlees_ES
dc.type.hasVersionAMes_ES
dspace.entity.typePublication

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