Publication:
Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk

Simple item page
dc.contributor.authorPapandreou, Christopher
dc.contributor.authorBabio, Nancy
dc.contributor.authorDíaz-López, Andrés
dc.contributor.authorMartínez-González, Miguel Á
dc.contributor.authorBecerra-Tomas, Nerea
dc.contributor.authorCorella, Dolores
dc.contributor.authorSchröder, Helmut
dc.contributor.authorRomaguera, Dora
dc.contributor.authorVioque, Jesús
dc.contributor.authorAlonso-Gómez, Ángel M
dc.contributor.authorWärnberg, Julia
dc.contributor.authorMartínez, Alfredo J
dc.contributor.authorSerra-Majem, Lluís
dc.contributor.authorEstruch, Ramon
dc.contributor.authorMuñoz-Garach, Araceli
dc.contributor.authorLapetra, José
dc.contributor.authorPintó, Xavier
dc.contributor.authorTur, Josep A
dc.contributor.authorGarcia-Rios, Antonio
dc.contributor.authorBueno-Cavanillas, Aurora
dc.contributor.authorDelgado-Rodríguez, Miguel
dc.contributor.authorMatía-Martín, Pilar
dc.contributor.authorDaimiel, Lidia
dc.contributor.authorM Sánchez, Vicente
dc.contributor.authorVidal, Josep
dc.contributor.authorVázquez, Clotilde
dc.contributor.authorRos, Emilio
dc.contributor.authorRuiz-Canela, Miguel
dc.contributor.authorBulló, Mónica
dc.contributor.authorSorli, Jose V
dc.contributor.authorQuifer, Mireia
dc.contributor.authorColom, Antoni
dc.contributor.authorOncina-Canovas, Alejandro
dc.contributor.authorT Sierra, Lucas
dc.contributor.authorBarón-López, Javier
dc.contributor.authorPérez-Farinós, Napoleón
dc.contributor.authorAbete, Itziar
dc.contributor.authorSanchez-Villegas, Almudena
dc.contributor.authorCasas, Rosa
dc.contributor.authorF García, José C
dc.contributor.authorSantos-Lozano, José M
dc.contributor.authorCorbella, Emili
dc.contributor.authorDel M Bibiloni, Maria
dc.contributor.authorDiez-Espino, Javier
dc.contributor.authorAsensio, Eva M
dc.contributor.authorTorras, Laura
dc.contributor.authorMorey, Marga
dc.contributor.authorCompañ-Gabucio, Laura
dc.contributor.authorS Lete, Itziar
dc.contributor.authorCenoz-Osinaga, Juan Carlos
dc.contributor.authorCastañer, Olga
dc.contributor.authorSalas-Salvadó, Jordi
dc.date.accessioned2024-02-10T20:01:06Z
dc.date.available2024-02-10T20:01:06Z
dc.date.issued2019-04-01
dc.description.abstractThe aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations (β = 0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio (β = 0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio.
dc.description.sponsorshipThe PREDIMED-Plus trial was supported by the official funding agency for biomedical research of the Spanish government, ISCIII, through the Fondo de Investigacion para la Salud (FIS), which is co-funded by the European Regional Development Fund (three coordinated FIS projects led by Jordi Salas-Salvado and Josep Vidal, including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926), the Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensives obre la actividad fisica Cohorte PREDIMED-PLUS grant to Jordi Salas-Salvado, the European Research Council (Advanced Research Grant 2013-2018; 340918) grant to Miguel Angel Martinez-Gonzalez, the Recercaixa grant to Jordi Salas-Salvado (2013ACUP00194), the grant from the Consejeria de Salud de la Junta de Andalucia (PI0458/2013; PS0358/2016), grants from the Consejeria de Salud de la Junta de Andalucia (PI0458/2013; PS0358/2016; PI0137/2018), the PROMETEO/2017/017 grant from the Generalitat Valenciana, the SEMERGEN grant, and FEDER funds (CB06/03). Olga Castaner was granted by the JR17/00022, ISCIII. Christopher Papandreou is supported by a postdoctoral fellowship granted by the Autonomous Government of Catalonia (PERIS 2016-2020 Incorporacio de Cientifics I Tecnolegs, SLT002/0016/00428). Jose C. Fernandez-Garcia is supported by a research contract from Servicio Andaluz de Salud (SAS) (B-0003-2017). None of the funding sources took part in the design, collection, analysis, or interpretation of the data, or in the decision to submit the manuscript for publication. The corresponding authors had full access to all the data in the study and had final responsibility forsubmitting for publication.
dc.format.number4es_ES
dc.format.volume11es_ES
dc.identifier.doi10.3390/nu11040761
dc.identifier.e-issn2072-6643es_ES
dc.identifier.journalNutrientses_ES
dc.identifier.otherhttp://hdl.handle.net/10668/13784
dc.identifier.otherhttp://hdl.handle.net/20.500.13003/17550
dc.identifier.pubmedID30939748es_ES
dc.identifier.puiL2001900059
dc.identifier.scopus2-s2.0-85064224623
dc.identifier.urihttp://hdl.handle.net/20.500.12105/17839
dc.identifier.wos467749800054
dc.language.isoeng
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectActigraphy
dc.subjectSerum uric acid
dc.subjectSerum uric acid to creatinine ratio
dc.subjectSleep duration
dc.subject.decsSueño
dc.subject.decsBiomarcadores
dc.subject.decsFemenino
dc.subject.decsÁcido úrico
dc.subject.decsMasculino
dc.subject.decsEstudios Transversales
dc.subject.decsFactores de Riesgo
dc.subject.decsHumanos
dc.subject.decsRegión Mediterránea
dc.subject.decsPersona de Mediana Edad
dc.subject.decsAnciano
dc.subject.decsEnfermedades Cardiovasculares
dc.subject.decsCreatinina
dc.subject.decsEspaña
dc.subject.meshAged
dc.subject.meshBiomarkers
dc.subject.meshCardiovascular Diseases
dc.subject.meshCreatinine
dc.subject.meshCross-Sectional Studies
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMediterranean Region
dc.subject.meshMiddle Aged
dc.subject.meshRisk Factors
dc.subject.meshSleep
dc.subject.meshSpain
dc.subject.meshUric Acid
dc.titleSleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk
dc.typeresearch article
dc.type.hasVersionVoR
dspace.entity.typePublication

Files

Collections

IBIMA-Plataforma BIONAND - Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (Andalucía)
IDIBAPS - Instituto de Investigaciones Biomédicas August Pi i Sunyer (Cataluña)
IdisBa - Instituto de Investigación Sanitaria Illes Balears (Baleares)
IdiSNA - Instituto de Investigación Sanitaria de Navarra (Navarra)
IdISSC - Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (Madrid)
IMIBIC - Instituto Maimónides de Investigación Biomédica de Córdoba (Andalucía)
Load more