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Circadian rhythms in thrombosis and atherothrombotic events.

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dc.contributor.authorPeñaloza-Martínez, Eduardo
dc.contributor.authorMoreno, Guillermo
dc.contributor.authorAroca-Crevillen, Alejandra
dc.contributor.authorHuertas, Sergio
dc.contributor.authorVicent, Lourdes
dc.contributor.authorRosillo, Nicolás
dc.contributor.authorHidalgo, Andres
dc.contributor.authorBueno, Hector
dc.date.accessioned2023-03-23T09:02:05Z
dc.date.available2023-03-23T09:02:05Z
dc.date.issued2022-02-11
dc.description.abstractBiological circadian rhythms in living organisms are regulated by molecular clocks. Several of these clocks are present in blood vessels, peripheral tissues, and immune cells. There is strong evidence linking dysregulation of circadian rhythms to the development of cardiovascular disease. Dysregulation of circadian rhythms is believed to activate inflammatory processes at specific times of day, leading to an increased risk of thrombosis and atherosclerosis progression. Research into circadian clock genes and molecular networks has the potential to identify therapeutic targets to reduce cardiovascular risk. In this review, we summarize the evidence linking circadian rhythms to thrombosis and atherothrombotic events and discuss potential therapeutic implications.es_ES
dc.description.peerreviewedSíes_ES
dc.description.sponsorshipThis research received no external funding.es_ES
dc.format.number2es_ES
dc.format.page51es_ES
dc.format.volume27es_ES
dc.identifier.citationFront Biosci (Landmark Ed). 2022 Feb 11;27(2):51es_ES
dc.identifier.doi10.31083/j.fbl2702051es_ES
dc.identifier.e-issn2768-6698es_ES
dc.identifier.journalFrontiers in bioscience (Landmark edition)es_ES
dc.identifier.pubmedID35226994es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/15692
dc.language.isoenges_ES
dc.publisherFrontiers Mediaes_ES
dc.relation.publisherversion10.31083/j.fbl2702051es_ES
dc.repisalud.institucionCNICes_ES
dc.repisalud.orgCNICCNIC::Grupos de investigación::Investigación Cardiovascular Traslacional Multidisciplinariaes_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.meshAtherosclerosises_ES
dc.subject.meshCardiovascular Diseaseses_ES
dc.subject.meshCircadian Clockses_ES
dc.subject.meshThrombosises_ES
dc.subject.meshCircadian Rhythmes_ES
dc.subject.meshHumanses_ES
dc.titleCircadian rhythms in thrombosis and atherothrombotic events.es_ES
dc.typereviewes_ES
dc.type.hasVersionVoRes_ES
dspace.entity.typePublication
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