Publication:
RAF1 kinase activity is dispensable for KRAS/p53 mutant lung tumor progression.

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dc.contributor.authorSanclemente, Manuel
dc.contributor.authorNieto, Patricia
dc.contributor.authorGarcia-Alonso, Sara
dc.contributor.authorFernández-García, Fernando
dc.contributor.authorDrosten, Matthias
dc.contributor.authorSantamaria, David
dc.contributor.authorMusteanu, Mónica
dc.contributor.authorGuerra, Carmen
dc.contributor.authorEsteban-Burgos, Laura
dc.contributor.authorCaleiras, E
dc.contributor.authorMartinez Torrecuadrada, Jorge Luis
dc.contributor.authorBarbacid, Mariano
dc.contributor.authorCaleiras, Eduardo
dc.contributor.authorMartinez-Torrecuadrada, Jorge
dc.contributor.funderUnión Europea. Comisión Europea. European Research Council (ERC)
dc.contributor.funderUnión Europea. Comisión Europea
dc.contributor.funderGovernment of Spain
dc.contributor.funderComunidad de Madrid (España)
dc.contributor.funderFundación AXA
dc.contributor.funderAsociación Española Contra el Cáncer
dc.date.accessioned2022-07-14T09:39:51Z
dc.date.available2022-07-14T09:39:51Z
dc.date.issued2021-01-28
dc.description.peerreviewedSíes_ES
dc.description.sponsorshipWe thank Dr. Shiva Malek and her colleagues (Genentech Inc.) for sharing their results with us before publication. We also thank M. San Roman, R. Villar, M.C. Gonzalez, A. Lopez, N. Cabrera, P. Villanueva, J. Condo, O. Dominguez, and S. Ortega for excellent technical support. This work was supported by grants from the European Research Council (ERC-2015-AdG/695566, THERACAN); the Spanish Ministry of Science, Innovation, and Universities (RTC-2017-6576-1 and RTI2018094664-B-I00) and the Autonomous Community of Madrid (B2017/BMD-3884 iLUNG-CM) to M.B., as well as by a grant from the Spanish Ministry of Science, Innovation and Universities (RTI2018-094664-B-I00) to M.B. and M.M. M.B. is a recipient of an Endowed Chair from the AXA Research Fund. M.S., P.N., and F.F.-G. were supported by FPU fellowships from the Spanish Ministry of Education. L.E.-B. was a recipient of an FPI fellowship from the Spanish Ministry of Economy and Competitiveness. S.G.-A. is a recipient of a postdoctoral fellowship from the Asociacion Espanola Contra el Cancer (AECC).es_ES
dc.format.number3es_ES
dc.format.page294-296es_ES
dc.format.volume39es_ES
dc.identifier.citationCancer Cell . 2021;39(3):294-296.es_ES
dc.identifier.doi10.1016/j.ccell.2021.01.008es_ES
dc.identifier.e-issn1878-3686es_ES
dc.identifier.issn1535-6108es_ES
dc.identifier.journalCancer celles_ES
dc.identifier.pubmedID33513349es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/14718
dc.language.isoenges_ES
dc.publisherCell Press
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/B2017/BMD-3884 iLUNG-CMes_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/RTC-2017-6576-1es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/RTI2018094664-B-I00es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/B2017/BMD-3884es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/695566/EUes_ES
dc.relation.publisherversionhttps://doi.org/10.1016/j.ccell.2021.01.008es_ES
dc.repisalud.institucionCNIOes_ES
dc.repisalud.orgCNIOCNIO::Grupos de investigación::Grupo de Oncología Experimentales_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAtribución-NoComercial-CompartirIgual 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectAPOPTOSISes_ES
dc.subjectREGRESSIONes_ES
dc.subjectC-RAFes_ES
dc.subject.meshAnimalses_ES
dc.subject.meshCell Line, Tumores_ES
dc.subject.meshDisease Progressiones_ES
dc.subject.meshHumanses_ES
dc.subject.meshLung Neoplasmses_ES
dc.subject.meshMutationes_ES
dc.subject.meshPhosphorylationes_ES
dc.subject.meshProto-Oncogene Proteinses_ES
dc.subject.meshProto-Oncogene Proteins c-rafes_ES
dc.subject.meshProto-Oncogene Proteins p21(ras)es_ES
dc.subject.meshTumor Suppressor Protein p53es_ES
dc.titleRAF1 kinase activity is dispensable for KRAS/p53 mutant lung tumor progression.es_ES
dc.typejournal articlees_ES
dc.type.hasVersionVoRes_ES
dspace.entity.typePublication
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