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Animal models of brain metastasis.

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dc.contributor.authorMiarka, Lauritz
dc.contributor.authorValiente, Manuel
dc.contributor.funderMinisterio de Ciencia e Innovación (España)
dc.contributor.funderFundacio La Marato de TV3
dc.contributor.funderFundacion Ramon Areces
dc.contributor.funderWorldwide Cancer Research
dc.contributor.funderAsociacion Espanola Contra el Cancer
dc.contributor.funderEuropean Research Council (ERC)
dc.contributor.funderBoehringer Ingelheim
dc.date.accessioned2024-12-04T13:12:02Z
dc.date.available2024-12-04T13:12:02Z
dc.date.issued2021-11
dc.description.abstractModeling of metastatic disease in animal models is a critical resource to study the complexity of this multi-step process in a relevant system. Available models of metastatic disease to the brain are still far from ideal but they allow to address specific aspects of the biology or mimic clinically relevant scenarios. We not only review experimental models and their potential improvements but also discuss specific answers that could be obtained from them on unsolved aspects of clinical management.
dc.description.peerreviewedSí
dc.description.tableofcontentsWork in the Brain Metastasis Group is supported by Ministerio de Ciencia e Innovacion (SAF2017-89643-R) (M.V.), Fundacio La Marato de TV3 (141) (M.V.), Fundacion Ramon Areces (CIVP19S8163) (M.V.), Worldwide Cancer Research (19-0177) (M.V.), H2020-FETOPEN (828972) (M.V.), Cancer Research Institute (Clinic and Laboratory Integration Program CRI Award 2018 (54545)) (M.V.), Asociacion Espanola Contra el Cancer (GCTRA16015SEOA, LABAE19002VALI) (M.V.), European Research Council (ERC CoG 864759) (M.V.), and a Boehringer Ingelheim Fonds MD fellowship (L.M.). M.V. is an EMBO YIP member (4053).
dc.format.number5
dc.format.pagev144-v156
dc.format.volume3
dc.identifier.citationNeurooncol Adv . 2021 Nov 27;3(Suppl 5):v144-v156.
dc.identifier.journalNeurooncol Adv
dc.identifier.pubmedID34859241
dc.identifier.urihttps://hdl.handle.net/20.500.12105/25856
dc.language.isoeng
dc.publisherOxford University Press
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/864759/EU
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/828972/EU
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2017-89643-R/ES/BIOLOGIA DE LOS ASTROCITOS REACTIVOS STAT3+ EN LA METASTASIS CEREBRAL/
dc.relation.publisherversionhttp://10.1093/noajnl/vdab115
dc.repisalud.institucionCNIO
dc.repisalud.orgCNIOCNIO::Grupos de investigación::Grupo de Metástasis Cerebral
dc.rights.accessRightsopen access
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectbrain metastasis
dc.subjectexperimental models
dc.subjecttherapy
dc.subjecttreatment toxicity
dc.titleAnimal models of brain metastasis.
dc.typeresearch article
dc.type.hasVersionVoR
dspace.entity.typePublication
relation.isAuthorOfPublication9ff41ae3-2484-4d1c-bfb4-9f7a64487317
relation.isAuthorOfPublication.latestForDiscovery9ff41ae3-2484-4d1c-bfb4-9f7a64487317

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