Publication:
Trends of non-lethal intentional self-harm and suicide in Spain 2018–2023: a nationwide registry-based study

dc.contributor.authorLopez-Cuadrado, Teresa
dc.contributor.authorMortier, Philippe
dc.contributor.authorAlonso, Jordi
dc.contributor.authorMartínez-Alés, Gonzalo
dc.contributor.funderInstituto de Salud Carlos III
dc.contributor.funderUnión Europea. Comisión Europea. NextGenerationEU
dc.contributor.funderAgència de Gestió d´Ajuts Universitaris i de Recerca (AGAUR)
dc.contributor.funderUnión Europea. Comisión Europea
dc.contributor.funderAmerican Foundation for Suicide Prevention
dc.contributor.funderNIH - National Institute of Mental Health (NIMH) (Estados Unidos)
dc.contributor.funderBrain and Behavior Research Foundation
dc.contributor.funderFundació la Marató de TV3
dc.date.accessioned2025-10-10T09:48:57Z
dc.date.available2025-10-10T09:48:57Z
dc.date.issued2025-11
dc.description.abstractBackground: Monitoring suicide and non-lethal intentional self-harm (NLISH) is critical for prevention efforts. We analysed trends in NLISH and suicide in Spain (2018–2023), including related demographic and clinical factors. Methods: Nationwide population-based study including all NLISH hospitalisations (from health registries) and suicides (from national mortality data) in Spain between 2018 and 2023. We first examined the sociodemographic characteristics and method used for both outcomes, and the clinical characteristics of NLISH hospitalisations. Then, we evaluated annual and monthly trends in NLISH and suicide rates overall and by sex and age group using Joinpoint regression. Findings: Between 2018 and 2023, we identified 73,692 NLISH hospitalisations and 23,496 suicides in Spain, averaging 12,282 and 3916 annually, respectively. NLISH hospitalisations were more common among women (n = 44,304; 60·1%), and suicides among men (n = 17,471; 74·4%). Youth aged 10–24 accounted for 17,915 (24·3%) NLISH hospitalisations but only 1125 (4·8%) suicides; conversely, individuals aged ≥65 represented 7327 (31·2%) suicides but only 9410 (12·8%) NLISH hospitalisations. The leading methods were drug poisoning for NLISH (n = 50,643; 68·7%) and hanging for suicide (n = 10,810; 46·0%). From 2018 to 2023, NLISH rates rose annually by 8·0% (95% CI: 1·5, 15·9), especially among young women shortly after the 2020 initial pandemic outbreak. Suicide rates rose 2·6% annually (95% CI: 0·6, 4·8), especially among young women and middle-aged men. Interpretation: Non-lethal self-harm is rising in Spain, especially among young women. Suicide shows smaller but significant increases. Urgent, age- and gender-sensitive strategies are needed to address all suicidal behaviour and ensure timely mental health care.
dc.description.peerreviewed
dc.description.sponsorshipDr López-Cuadrado's work is funded by a grant from the Instituto de Salud Carlos III PI23CIII/00056; Dr Mortier's work is funded by a Miguel Servet grant CP21/00078 funded by the Instituto de Salud Carlos III (ISCIII) and co-funded by the European Union; project grant AC22/00006, supported by ISCIII, and by the European Union NextGenerationEU, Mecanismo para la Recuperación y la Resiliencia (MRR), under the frame of ERA PerMed; project grant PI22/00107, funded by ISCIII and co-funded by the European Union; and project grant 202220-30 from the Fundació la Marató de TV3. Dr Alonso was supported by PI17/00521, funded by Instituto de Salud Carlos III (ISCIII) and co-funded by the European Union and AGAUR 2021 SGR 00624. Dr. Martínez-Alés's work is funded by grants from the American Foundation for Suicide Prevention (AFSP) (ECR-1-101-23), the Brain and Behavior Research Foundation (BBRF) (NARSAD 31312) and the National Institute of Mental Health (NIMH) (1R25MH129256-01A1).
dc.format.page101467
dc.format.volume58
dc.identifier.citationLópez-Cuadrado T, Mortier P, Alonso J, Martínez-Alés G. Trends of non-lethal intentional self-harm and suicide in Spain 2018–2023: a nationwide registry-based study. The Lancet Regional Health - Europe [Internet]. 2025 Nov;58:101467. Available from: http://dx.doi.org/10.1016/j.lanepe.2025.101467
dc.identifier.doi10.1016/j.lanepe.2025.101467
dc.identifier.journalThe Lancet Regional Health - Europe
dc.identifier.urihttps://hdl.handle.net/20.500.12105/26928
dc.language.isoeng
dc.publisherElsevier
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Proyectos de I+D+I en salud (AESI 2023)/PI23CIII%2F00056/ES/Trastornos psicóticos en España: estudio poblacional de la incidencia, factores de riesgo asociados, conductas suicidas e impacto en los recursos sanitarios/
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/ERA PerMed/AC22%2F00006///
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Proyectos de I+D+I en salud (AES 2022)/PI22%2F00107/ES/Hacia la prevención personalizada del suicidio: mejorar la evaluación del riesgo clínico y la asignación del tratamiento indicado entre los pacientes con riesgo de suicidio/RECIPROC
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia. Subprograma Estatal de Generación de Conocimiento. Proyectos de investigación en salud (AES 2017)/PI17%2F00521/ES/Incidencia poblacional de la tentativa y de la repetición de tentativa de suicidio: evaluación del Código riesgo suicidio de Cataluña/
dc.relation.projectIDinfo:eu-repo/grantAgreement/Fundación la Mataró de TV3//202220-30///
dc.relation.projectIDinfo:eu-repo/grantAgreement/American Foundation for Suicide Prevention//ECR-1-101-23///
dc.relation.projectIDinfo:eu-repo/grantAgreement/Agència de Gestió d´Ajuts Universitaris i de Recerca//SGR 00624///
dc.relation.projectIDinfo:eu-repo/grantAgreement/Brain and Behavior Research Foundation//NARSAD 31312///
dc.relation.projectIDinfo:eu-repo/grantAgreement/National Institute of Mental Health//1R25MH129256-01A1///
dc.relation.publisherversionhttps://doi.org/10.1016/j.lanepe.2025.101467
dc.repisalud.centroISCIII::Centro Nacional de Epidemiología (CNE)
dc.repisalud.institucionISCIII
dc.repisalud.instituteIIS::IMIM - Instituto Hospital del Mar de Investigaciones Médicas (Cataluña)
dc.repisalud.instituteIIS::IdiPAZ - Instituto de Investigación Sanitaria Hospital La Paz (Madrid)
dc.rights.accessRightsopen access
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectSuicide
dc.subjectNon-lethal intentional self-harm
dc.subjectSpain
dc.subjectAge trends
dc.subject.meshSuicide
dc.subject.meshSpain
dc.subject.meshSelf-Injurious Behavior
dc.subject.meshSuicidal Ideation
dc.subject.meshMental Health
dc.subject.meshPandemics
dc.subject.meshRegistries
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshFemale
dc.subject.meshAdolescent
dc.subject.meshMiddle Aged
dc.titleTrends of non-lethal intentional self-harm and suicide in Spain 2018–2023: a nationwide registry-based study
dc.typeresearch article
dc.type.hasVersionVoR
dspace.entity.typePublication
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