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Is Parental Longevity Associated With the Cardiovascular Risk and the Successful Aging of Their Offspring? Results From the Multinational MEDIS Study

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dc.contributor.authorTyrovolas, Stefanos
dc.contributor.authorPolychronopoulos, Evangelos
dc.contributor.authorMariolis, Anargiros
dc.contributor.authorPiscopo, Suzanne
dc.contributor.authorValacchi, Giuseppe
dc.contributor.authorMakri, Kornilia
dc.contributor.authorZeimbekis, Akis
dc.contributor.authorTyrovola, Dimitra
dc.contributor.authorBountziouka, Vassiliki
dc.contributor.authorGotsis, Efthimios
dc.contributor.authorMetallinos, George
dc.contributor.authorTur, Josep A
dc.contributor.authorMatalas, Antonia
dc.contributor.authorLionis, Christos
dc.contributor.authorHaro, Josep Maria
dc.contributor.authorPanagiotakos, Demosthenes B
dc.date.accessioned2024-07-11T09:12:16Z
dc.date.available2024-07-11T09:12:16Z
dc.date.issued2017-02
dc.description.abstractThe aim of the present study was to evaluate the role of parental longevity and parental cardiovascular disease (CVD) history in CVD risk and successful aging of a random sample of older adults living in the Mediterranean basin and who participated in the MEDiterranean Islands (MEDIS) study. During 2005 to 2011, 2663 elders were voluntarily enrolled. A multidimensional successful aging index consisting of 10 components was used. Paternal and maternal longevity was defined as those older participants of whom both parents lived above the age of 90. The burden of CVD-related factors (CVD-RFs) was calculated as the total score of 4 major CVD-RFs (range 0-4). After adjustment, parental longevity was inversely associated with the burden of CVD-RFs (P = .04). Moreover, parental longevity was positively associated with the older adults' successful aging score (-coefficient [95% confidence interval]: .38 [0.06-0.71]). Parent's long living was revealed as an important factor for successful aging and for reduced CVD risk, suggesting that further research is needed in the genetic predisposition of longevity.en
dc.description.sponsorshipThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The study was funded by research grants from the Hellenic Heart Foundation, and therefore, we would also like to thank Prof Pavlos Toutouzas, Director of the Foundation. Stefano Tyrovola's work was supported by the Foundation for Education and European Culture (IPEP), the Sara Borrell postdoctoral program (reference no. CD15/00019 from the Instituto de Salud Carlos III (ISCIII-Spain), and the Fondos Europeo de Desarrollo Regional (FEDER). Josep A. Tur was funded by grants PI11/01791, CIBERobn CB12/03/30038, and CAIB/EU 35/2001.es_ES
dc.format.number2es_ES
dc.format.page124-131es_ES
dc.format.volume68es_ES
dc.identifier.citationTyrovolas Stefanos, Polychronopoulos Evangelos, Mariolis Anargiros, Piscopo Suzanne, Valacchi Giuseppe, Makri Kornilia, et al. Is Parental Longevity Associated With the Cardiovascular Risk and the Successful Aging of Their Offspring? Results From the Multinational MEDIS Study. Angiology. 2017 Feb;68(2):124-131. Epub 2016 Jul 11.en
dc.identifier.doi10.1177/0003319716642140
dc.identifier.e-issn1940-1574es_ES
dc.identifier.issn0003-3197
dc.identifier.journalAngiologyes_ES
dc.identifier.otherhttp://hdl.handle.net/20.500.13003/9965
dc.identifier.pubmedID27069110es_ES
dc.identifier.puiL613905321
dc.identifier.scopus2-s2.0-85007343613
dc.identifier.urihttp://hdl.handle.net/20.500.12105/20484
dc.identifier.wos391460300006
dc.language.isoengen
dc.publisherSAGE Publishing
dc.relation.publisherversionhttps://dx.doi.org/10.1177/0003319716642140en
dc.rights.accessRightsopen accessen
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectParental longevity
dc.subjectSuccessful aging
dc.subjectCardiovascular disease
dc.subjectOlder adults
dc.subjectMediterranean basin
dc.subject.decsPadres*
dc.subject.decsFactores de Riesgo*
dc.subject.decsHumanos*
dc.subject.decsAnciano de 80 o más Años*
dc.subject.decsFemenino*
dc.subject.decsEnfermedades Cardiovasculares*
dc.subject.decsLongevidad*
dc.subject.decsIslas del Mediterráneo*
dc.subject.decsMasculino*
dc.subject.meshCardiovascular Diseases*
dc.titleIs Parental Longevity Associated With the Cardiovascular Risk and the Successful Aging of Their Offspring? Results From the Multinational MEDIS Studyen
dc.typeresearch articleen
dc.type.hasVersionSMURes_ES
dspace.entity.typePublication
relation.isPublisherOfPublicationdfa013d1-54c0-41b6-acc8-4fea39092dc7
relation.isPublisherOfPublication.latestForDiscoverydfa013d1-54c0-41b6-acc8-4fea39092dc7

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