Publication:
p38γ/δ activation alters cardiac electrical activity and predisposes to ventricular arrhythmia

Simple item page
dc.contributor.authorRomero-Becerra, Rafael
dc.contributor.authorCruz, Francisco M.
dc.contributor.authorMora, Alfonso
dc.contributor.authorLopez, Juan Antonio
dc.contributor.authorPonce-Balbuena, Daniela
dc.contributor.authorAllan, Andrew
dc.contributor.authorRamos-Mondragón, Roberto
dc.contributor.authorGonzalez-Teran, Barbara
dc.contributor.authorLeón, Marta
dc.contributor.authorRodríguez, Maria Elena
dc.contributor.authorLeiva-Vega, Luis
dc.contributor.authorGuerrero-Serna, Guadalupe
dc.contributor.authorJimenez-Vazquez, Eric N.
dc.contributor.authorFilgueiras-Rama, David
dc.contributor.authorVazquez, Jesus
dc.contributor.authorJalife, Jose
dc.contributor.authorSabio, Guadalupe
dc.date.accessioned2023-12-04T10:05:36Z
dc.date.available2023-12-04T10:05:36Z
dc.date.issued2023
dc.description.peerreviewedSíes_ES
dc.description.sponsorshipWe gratefully acknowledge L. Sen-Martín, J. Alegre-Cebollada (CNIC, Madrid) and L. Carrier (University Medical Center HamburgEppendorf and DZHK, Hamburg) for the cMyBP3-C KO cardiac tissue; D. Roiz-Valle and C. López-Otín (IUOPA; Universidad de Oviedo, Oviedo) for the LmnaG609G/G609G cardiac tissue; and R. J. Davis for the MKK6 KO mice. We thank G. Giovinazzo and the CNIC Pluripotent Cell Technology Unit (CNIC, Madrid) for the hiPSCs. We thank S. Bartlett and F. Chanut (CNIC, Madrid) for English editing, and R. R. Mondragon (University of Michigan, Ann Arbor) for technical support. We are grateful to R. J. Davis (University of Massachusetts Chan Medical School, Worcester), A. Padmanabhan (University of California, San Francisco) and M. Costa and C. López-Otín (IUOPA; Universidad de Oviedo, Oviedo) for critical reading of the manuscript. We thank the staf at the CNIC Genomics and Bioinformatics Units for technical support and help with data analysis and A. C. Silva for help with figure editing and design. This work was funded by a CNIC Intramural Project Severo Ochoa (Expediente 12- 2016 IGP) to G.S. and J.J. G.S. is supported by the following projects: PMP21/00057 IMPACT-2021, funded by the Instituto de Salud Carlos III (ISCIII), and PDC2021-121147-I00 and PID2019-104399RB-I00, funded by MCIN/AEI/10.13039/501100011033—all funded by the European Union (FEDER/FSE); ‘Una manera de hacer Europa’/‘El FSE invierte en tu futuro’/Next Generation EU and co-funded by the European Union/Plan de Recuperación, Transformación y Resiliencia (PRTR). R.R.B. is a fellow of the FPU Program (FPU17/03847). B.G.T. was a fellow of the FPI Severo Ochoa CNIC Program (SVP‐2013‐067639) and an American Heart Association Postdoctoral Fellow (18POST34080175). The following grants provided additional funding: Instituto de Salud Carlos III, PDC2021-121147-I00 Convocatoria: Proyectos Prueba de Concepto 2021 Ministerio de Ciencia e Innovación and PID2022-138525OB-I00 Ministerio de Ciencia e Innovación; US National Heart, Lung, and Blood Institute (R01 grant HL122352); Fondos FEDER, Madrid, Spain, and Fundación Bancaria ‘La Caixa (project HR19/52160013) to J.J.; American Heart Association Postdoctoral Fellowship 14POST17820005 to D.P.B.; and MICINN PGC2018-097019-B-I00, ISCIII-SGEFI/ERDF (PRB3-IPT17/0019, ProteoRed), the Fundació Marató TV3 (grant 122/C/2015) and ‘la Caixa’ Banking Foundation (project code HR17- 00247) to J.V. The CNIC is supported by the Instituto de Salud Carlos III (ISCIII), the Ministerio de Ciencia e Innovación (MCIN) and the Pro CNIC Foundation and is a Severo Ochoa Center of Excellence (grant CEX2020-001041-S, funded by MICIN/AEI/10.13039/501100011033).es_ES
dc.identifier.citationNat Cardiovasc Res (2023).es_ES
dc.identifier.doi10.1038/s44161-023-00368-xes_ES
dc.identifier.e-issn2731-0590es_ES
dc.identifier.journalNature Cardiovascular Researches_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/16743
dc.language.isoenges_ES
dc.publisherNature Publishing Groupes_ES
dc.repisalud.institucionCNICes_ES
dc.repisalud.orgCNICCNIC::Grupos de investigación::Arritmias Cardíacases_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titlep38γ/δ activation alters cardiac electrical activity and predisposes to ventricular arrhythmiaes_ES
dc.typejournal articlees_ES
dc.type.hasVersionVoRes_ES
dspace.entity.typePublication
relation.isAuthorOfPublicationbc42fc37-5614-4176-852f-4210784143e8
relation.isAuthorOfPublicationd79f2bf1-6f13-4b5f-9ae3-4c0ea06e9dcb
relation.isAuthorOfPublication0dc71b91-44e2-461b-8cef-e13b10191736
relation.isAuthorOfPublication765eed5e-47c5-408b-b169-4aebaf54059a
relation.isAuthorOfPublication5f52deb0-3320-4bb1-ae0d-92513bea3cba
relation.isAuthorOfPublication9743763b-919c-4fa9-a53c-57c41be5e0ac
relation.isAuthorOfPublication3281dd95-3aa7-46b8-857c-aca343b747c0
relation.isAuthorOfPublication7de1300f-8563-434d-b693-41b7c8c6fdd1
relation.isAuthorOfPublication.latestForDiscoverybc42fc37-5614-4176-852f-4210784143e8

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Activation alters cardiac_nature cardiovascular research_2023.pdf
Size:
8.34 MB
Format:
Adobe Portable Document Format
Description:
Artículo
Download

Collections

Grupos de investigación