Publication:
Production of HlyA and ClyA haemolysins among quinolone-resistant Escherichia coli isolated from clinical samples

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dc.contributor.authorMarquez-Lopez, Alicia
dc.contributor.authorRuiz Del Castillo, Belen
dc.contributor.authorCano, María Eliecer
dc.contributor.authorRodríguez-Mirones, Cristina
dc.contributor.authorOteo-Iglesias, Jesus
dc.contributor.authorSáez, David
dc.contributor.authorMartínez-Martínez, Luis
dc.contributor.funderInstituto de Salud Carlos III
dc.contributor.funderUnión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
dc.date.accessioned2018-11-14T11:44:16Z
dc.date.available2018-11-14T11:44:16Z
dc.date.issued2013-12
dc.description.abstractMost Escherichia coli resistant to quinolones are not haemolytic. The objective of this study was to determine the phylogroup, clonal relationship, mechanism of quinolone resistance and virulence factors in 70 haemolytic E. coli resistant to nalidixic acid. Sixty-six isolates contained the hlyA gene, belonged to phylogroup B2, and 61 of them presented low-level resistance to fluoroquinolones. Four isolates presented high-level resistance to fluoroquinolones, contained the clyA gene and were included in phylogroup D. One single isolate (phylogroup D, with low level resistance to fluoroquinolones) contained both cytotoxins.es_ES
dc.description.peerreviewedSíes_ES
dc.description.sponsorshipSupported by Ministerio de Economía y Competitividad, Instituto de Salud Carlos III, Madrid, Spain, co-financed by European Development Regional Fund “A way to achieve Europe” ERDF, Spanish Network for the Research in Infectious Diseases (REIPI RD12/0015). Alicia Márquez-López was supported by the REIPI and has been supported by a grant from the Instituto de Formación e Investigación Marqués de Valdecilla (IFIMAV), Santander, Spain. We want to thank Eduardo López for his review of English version of the manuscript.es_ES
dc.format.number1es_ES
dc.format.page71es_ES
dc.format.volume2es_ES
dc.identifier.citationSpringerplus. 2013;2(1):71.es_ES
dc.identifier.doi10.1186/2193-1801-2-71es_ES
dc.identifier.issn2193-1801es_ES
dc.identifier.journalSpringerPluses_ES
dc.identifier.pubmedID23543875es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/6588
dc.language.isoenges_ES
dc.publisherSpringeres_ES
dc.relation.publisherversionhttps://www.doi.org/10.1186/2193-1801-2-71es_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAtribución- 2.0 Internacional*
dc.rights.urihttps://creativecommons.org/licenses/by/2.0/*
dc.subjectEscherichia colies_ES
dc.subjectHaemolysises_ES
dc.subjectQuinolone resistancees_ES
dc.subjectclyAes_ES
dc.subjecthlyAes_ES
dc.titleProduction of HlyA and ClyA haemolysins among quinolone-resistant Escherichia coli isolated from clinical sampleses_ES
dc.typejournal articlees_ES
dc.type.hasVersionVoRes_ES
dspace.entity.typePublication
relation.isAuthorOfPublication4ac67376-8b3e-48bd-9415-8770421fdd67
relation.isAuthorOfPublication.latestForDiscovery4ac67376-8b3e-48bd-9415-8770421fdd67

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