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cDC1s: New Orchestrators of Tissue Innate Immunity

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dc.contributor.authordel Fresno, Carlos
dc.contributor.authorSancho, David
dc.contributor.funderAsociación Española Contra el Cáncer
dc.contributor.funderMinisterio de Economía, Industria y Competitividad (España)
dc.contributor.funderUnión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
dc.contributor.funderComunidad de Madrid (España)
dc.contributor.funderInstituto de Salud Carlos III
dc.contributor.funderFondation ACTERIA (Acting on European Research in Immunology and Allergology)
dc.contributor.funderFundación La Marató TV3
dc.contributor.funderUnión Europea. Comisión Europea
dc.contributor.funderUnión Europea. Comisión Europea. European Research Council (ERC)
dc.contributor.funderFundación ProCNIC
dc.date.accessioned2019-07-03T13:36:22Z
dc.date.available2019-07-03T13:36:22Z
dc.date.issued2019-07
dc.description.abstractType-I conventional dendritic cells (cDC1s) are key in inducing adaptive immunity. Using single-cell sequencing, Ginhoux and colleagues (Immunity 2019;50:1069-1083.e8) find that a subset of activated cDC1s in bacteria-infected skin is critical for neutrophil recruitment via the production of VEGF-α. These results reveal a crucial function for cDC1s beyond antigen presentation.es_ES
dc.description.peerreviewedSíes_ES
dc.description.sponsorshipC.d.F. is supported by AECC Foundation as recipient of an ‘Ayuda Fundación Científica AECC a personal investigador en cancer’. Work in the D.S. laboratory is funded by the CNIC and grant SAF2016-79040-R from the Spanish Ministry of Economy, Industry and Competitiveness (MINECO), Agencia Estatal de Investigación and FEDER (European Fund for Regional Development); B2017/BMD-3733 Immunothercan-CM from Comunidad de Madrid; RD16/0015/0018-REEM from FIS-Instituto de Salud Carlos III, MINECO and FEDER; Foundation Acteria; Constantes y Vitales prize (Atresmedia); Foundation La Marató de TV3 (201723); the European Commission (635122-PROCROP H2020) and the European Research Council (ERCConsolidator Grant 725091). The CNIC is supported by the MINECO and the Pro-CNIC Foundation, and is a Severo Ochoa Center of Excellence (MINECO award SEV-2015-0505).es_ES
dc.format.number7es_ES
dc.format.page559-561es_ES
dc.format.volume40es_ES
dc.identifier.citationTrends Immunol. 2019; 40(7):559-561es_ES
dc.identifier.doi10.1016/j.it.2019.05.002es_ES
dc.identifier.e-issn1471-4981es_ES
dc.identifier.issn1471-4906es_ES
dc.identifier.journalTrends in immunologyes_ES
dc.identifier.pubmedID31133464es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/7846
dc.language.isoenges_ES
dc.publisherCell Presses_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/SAF2016-79490-Res_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/RD16/0015/0018-REEMes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/635122es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/725091es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/SEV-2015-0505es_ES
dc.relation.publisherversionhttps://doi.org/10.1016/j.it.2019.05.002es_ES
dc.repisalud.institucionCNICes_ES
dc.repisalud.orgCNICCNIC::Grupos de investigación::Inmunobiologíaes_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titlecDC1s: New Orchestrators of Tissue Innate Immunityes_ES
dc.typejournal articlees_ES
dc.type.hasVersionAMes_ES
dspace.entity.typePublication
relation.isAuthorOfPublicationc56ae6c1-121b-4e6c-ab1c-ae787f8622f2
relation.isAuthorOfPublication58aa2591-8084-4500-bfe4-8f2c54e398e9
relation.isAuthorOfPublication.latestForDiscoveryc56ae6c1-121b-4e6c-ab1c-ae787f8622f2

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