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Molecular Detection and Characterization of Intestinal and Blood Parasites in Wild Chimpanzees (Pan troglodytes verus) in Senegal

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dc.contributor.authorKöster, Pamela Carolina
dc.contributor.authorRenelies-Hamilton, Justinn
dc.contributor.authorDotras, Laia
dc.contributor.authorLlana, Manuel
dc.contributor.authorVinagre-Izquierdo, Celia
dc.contributor.authorPrakas, Petras
dc.contributor.authorSneideris, Donatas
dc.contributor.authorDashti, Alejandro
dc.contributor.authorBailo-Barroso, Begoña
dc.contributor.authorLanza-Suarez, Marta
dc.contributor.authorJiménez-Mejías, Alejandra
dc.contributor.authorMuñoz García, Carlota
dc.contributor.authorMuadica, Aly Salimo
dc.contributor.authorGonzalez-Barrio, David
dc.contributor.authorRubio Muñoz, Jose Miguel
dc.contributor.authorFuentes Corripio, Isabel
dc.contributor.authorPonce-Gordo, Francisco
dc.contributor.authorCalero-Bernal, Rafael
dc.contributor.authorCarmena, David
dc.contributor.authorBailo-Barroso
dc.contributor.funderMinisterio de Economía y Competitividad (España)es_ES
dc.contributor.funderInstituto de Salud Carlos IIIes_ES
dc.date.accessioned2022-07-20T11:30:20Z
dc.date.available2022-07-20T11:30:20Z
dc.date.issued2021-11-17
dc.description.abstractWild chimpanzee populations in West Africa (Pan troglodytes verus) have dramatically decreased as a direct consequence of anthropogenic activities and infectious diseases. Little information is currently available on the epidemiology, pathogenic significance, and zoonotic potential of protist species in wild chimpanzees. This study investigates the occurrence and genetic diversity of intestinal and blood protists as well as filariae in faecal samples (n = 234) from wild chimpanzees in the Dindefelo Community Nature Reserve, Senegal. PCR-based results revealed the presence of intestinal potential pathogens (Sarcocystis spp.: 11.5%; Giardia duodenalis: 2.1%; Cryptosporidium hominis: 0.9%), protist of uncertain pathogenicity (Blastocystis sp.: 5.6%), and commensal species (Entamoeba dispar: 18.4%; Troglodytella abrassarti: 5.6%). Entamoeba histolytica, Enterocytozoon bieneusi, and Balantioides coli were undetected. Blood protists including Plasmodium malariae (0.4%), Trypanosoma brucei (1.3%), and Mansonella perstans (9.8%) were also identified. Sanger sequencing analyses revealed host-adapted genetic variants within Blastocystis, but other parasitic pathogens (C. hominis, P. malariae, T. brucei, M. perstans) have zoonotic potential, suggesting that cross-species transmission between wild chimpanzees and humans is possible in areas where both species overlap. Additionally, we explored potential interactions between intestinal/blood protist species and seasonality and climate variables. Chimpanzees seem to play a more complex role on the epidemiology of pathogenic and commensal protist and nematode species than initially anticipated.es_ES
dc.description.peerreviewedSíes_ES
dc.description.sponsorshipThis research was funded by the Health Institute Carlos III (ISCIII), Ministry of Economy and Competitiveness (Spain), under project PI16CIII/00024.es_ES
dc.format.number11es_ES
dc.format.page3291es_ES
dc.format.volume11es_ES
dc.identifier.citationAnimals (Basel). 2021 Nov 17;11(11):3291.es_ES
dc.identifier.doi10.3390/ani11113291es_ES
dc.identifier.issn2076-2615es_ES
dc.identifier.journalAnimals (Basel)es_ES
dc.identifier.pubmedID34828022es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/14754
dc.language.isoenges_ES
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI16CIII/00024es_ES
dc.relation.publisherversionhttps://doi.org/10.3390/ani11113291es_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectPCRes_ES
dc.subjectEpidemiologyes_ES
dc.subjectNon-human primateses_ES
dc.subjectProtistses_ES
dc.subjectSeasonalityes_ES
dc.subjectZoonoseses_ES
dc.subjectConservationes_ES
dc.subjectEndangeredes_ES
dc.subjectGenotypinges_ES
dc.titleMolecular Detection and Characterization of Intestinal and Blood Parasites in Wild Chimpanzees (Pan troglodytes verus) in Senegales_ES
dc.typejournal articlees_ES
dc.type.hasVersionVoRes_ES
dspace.entity.typePublication
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