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BMPing up endocardial angiogenesis to generate coronary vessels.

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BMPing up endocardial_Dev Cell_2022.pdf (483.21 KB)
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URI: http://hdl.handle.net/20.500.12105/16832
DOI: 10.1016/j.devcel.2022.11.001

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2022-11-21

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Cell Press
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Abstract

Understanding how coronary vessels develop is important for designing better strategies to repair ischemic hearts. In this issue of Developmental Cell, D'Amato et al. report that BMP2 and CXCL12/CXCR4 act sequentially on endocardial cells to drive coronary angiogenesis and artery morphogenesis.

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Coronary Vessels Endocardium Humans Neovascularization, Pathologic Heart Morphogenesis

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Dev Cell. 2022 Nov 21;57(22):2515-2516.

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10.1016/j.devcel.2022.11.001

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editorial