Publication: Early estimates of the effectiveness of the 2011/12 influenza vaccine in the population targeted for vaccination in Spain, 25 December 2011 to 19 February 2012
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Jimenez-Jorge, Silvia ISCIII 
Mateo-Ontañon, Salvador de ISCIII
Pozo Sanchez, Francisco ISCIII
Casas Flecha, Inmaculada ISCIII
Garcia-Cenoz, Manuel ISCIII
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Abstract
We present early estimates of influenza vaccine effectiveness (VE) in the population targeted for vaccination, during 25 December 2011 to 19 February 2012. The adjusted VE was 55% (95% CI: 3 to 79) against any type of influenza virus and 54% (95% CI: 1 to 79) against influenza A(H3N2) virus. This suggests a moderate protective effect of the vaccine in the targeted population in a late influenza epidemic with limited match between vaccine and circulating strains.
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Euro Surveill. 2012 Mar 22;17(12). pii: 20129.