Publication:
A mechanistic view of the use of cold temperature in the treatment of cancer.

Simple item page
dc.contributor.authorGrazioso, Tatiana P
dc.contributor.authorDjouder, Nabil
dc.date.accessioned2024-02-08T21:35:08Z
dc.date.available2024-02-08T21:35:08Z
dc.date.issued2023-04-21
dc.description.abstractIn their latest article, Seki and colleagues investigate the potential role of cold as a therapeutical option to treat various cancer types, including even clinically untreatable cancers such as pancreatic cancers. The authors suggest that cold exposure may have a tumor-suppressive effect mediated by the activation of brown adipose tissue (BAT), in charge of dissipating heat through non-shivering thermogenesis. In this regard, circulating blood glucose is decreased, restricting the tumor glucose uptake, which is redistributed, favoring BAT uptake to fuel thermogenesis.1.es_ES
dc.description.peerreviewedSíes_ES
dc.description.sponsorshipThis work was funded by grants to N.D., supported by the State Research Agency (AEI, 10.13039/501100011033) from the Spanish Ministry of Science and Innovation (PID2021-122695OB-I00) , cofunded by European Regional Development Fund (ERDF) and by the Asociacion Espanola Contrael Cancer (AECC) (PRYGN211184DJOU) . This work was developed at the CNIO, funded by the Health Institute Carlos III (ISCIII) and the Spanish Ministry of Science and Innovation.es_ES
dc.format.number4es_ES
dc.format.page106511es_ES
dc.format.volume26es_ES
dc.identifier.citationiScience . 2023;26(4):106511.es_ES
dc.identifier.doi10.1016/j.isci.2023.106511es_ES
dc.identifier.e-issn2589-0042es_ES
dc.identifier.journaliSciencees_ES
dc.identifier.pubmedID37091251es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/17672
dc.language.isoenges_ES
dc.publisherCell Press
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PID2021-122695OB-I00es_ES
dc.relation.publisherversionhttps://doi.org/10.1016/j.isci.2023.106511.es_ES
dc.repisalud.institucionCNIOes_ES
dc.repisalud.orgCNIOCNIO::Grupos de investigación::Grupo de Factores de Crecimiento, Nutrientes y Cánceres_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleA mechanistic view of the use of cold temperature in the treatment of cancer.es_ES
dc.typejournal articlees_ES
dc.type.hasVersionVoRes_ES
dspace.entity.typePublication
relation.isAuthorOfPublicatione029ea8d-a728-41e5-8035-40ace0841d69
relation.isAuthorOfPublication.latestForDiscoverye029ea8d-a728-41e5-8035-40ace0841d69
relation.isPublisherOfPublicationaea619d1-42a6-47f8-84e2-6bc27d6f8300
relation.isPublisherOfPublication.latestForDiscoveryaea619d1-42a6-47f8-84e2-6bc27d6f8300

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Amechanisticview_2023.pdf
Size:
1.89 MB
Format:
Adobe Portable Document Format
Description:
Artículo principal
Download

Collections

Grupos de investigación