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Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

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dc.contributor.authorPeinado, Héctor
dc.contributor.authorOlmeda, David
dc.contributor.authorCano, Amparo
dc.date.accessioned2024-02-05T09:22:52Z
dc.date.available2024-02-05T09:22:52Z
dc.date.issued2007-06
dc.description.abstractThe molecular mechanisms that underlie tumour progression are still poorly understood, but recently our knowledge of particular aspects of some of these processes has increased. Specifically, the identification of Snail, ZEB and some basic helix-loop-helix (bHLH) factors as inducers of epithelial-mesenchymal transition (EMT) and potent repressors of E-cadherin expression has opened new avenues of research with potential clinical implications.es_ES
dc.description.peerreviewedNoes_ES
dc.format.number6es_ES
dc.format.page415es_ES
dc.format.volume7es_ES
dc.identifier.citationNat Rev Cancer. 2007;7(6):415-28es_ES
dc.identifier.doi10.1038/nrc2131es_ES
dc.identifier.issn1474-175Xes_ES
dc.identifier.journalNature reviews. Canceres_ES
dc.identifier.pubmedID17508028es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/17456
dc.language.isoenges_ES
dc.publisherNature Publishing Group
dc.relation.publisherversionhttps://doi.org/ 10.1038/nrc2131.es_ES
dc.repisalud.institucionCNIOes_ES
dc.repisalud.orgCNIOCNIO::Grupos de investigación::Grupo de Microambiente y Metástasises_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.meshNeoplasm Invasivenesses_ES
dc.subject.meshCadherinses_ES
dc.subject.meshCell Adhesiones_ES
dc.subject.meshCell Movementes_ES
dc.subject.meshDisease Progressiones_ES
dc.subject.meshEpitheliumes_ES
dc.subject.meshHelix-Turn-Helix Motifses_ES
dc.subject.meshHomeodomain Proteinses_ES
dc.subject.meshHumanses_ES
dc.subject.meshModels, Biologicales_ES
dc.subject.meshNeoplasmses_ES
dc.subject.meshPhenotypees_ES
dc.subject.meshProtein Processing, Post-Translationales_ES
dc.subject.meshRepressor Proteinses_ES
dc.subject.meshSignal Transductiones_ES
dc.subject.meshSnail Family Transcription Factorses_ES
dc.subject.meshTranscription Factorses_ES
dc.subject.meshZinc Finger E-box-Binding Homeobox 1es_ES
dc.titleSnail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?es_ES
dc.typejournal articlees_ES
dc.type.hasVersionSMURes_ES
dspace.entity.typePublication
relation.isAuthorOfPublicationd09f9f55-7728-4d6e-bd44-64fe8e84c56c
relation.isAuthorOfPublication.latestForDiscoveryd09f9f55-7728-4d6e-bd44-64fe8e84c56c
relation.isPublisherOfPublication301fb00e-338e-4f8c-beaa-f9d8f4fefcc0
relation.isPublisherOfPublication.latestForDiscovery301fb00e-338e-4f8c-beaa-f9d8f4fefcc0

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