Publication:
Platelet-Derived Extracellular Vesicles for Regenerative Medicine

Simple item page
dc.contributor.authorAntich-Rosselló, Miquel
dc.contributor.authorForteza-Genestra, Maria Antonia
dc.contributor.authorMonjo, Marta
dc.contributor.authorRamis, Joana Maria
dc.date.accessioned2024-09-18T06:43:54Z
dc.date.available2024-09-18T06:43:54Z
dc.date.issued2021-08
dc.description.abstractExtracellular vesicles (EVs) present a great potential for the development of new treatments in the biomedical field. To be used as therapeutics, many different sources have been used for EVs obtention, while only a few studies have addressed the use of platelet-derived EVs (pEVs). In fact, pEVs have been shown to intervene in different healing responses, thus some studies have evaluated their regenerative capability in wound healing or hemorrhagic shock. Even more, pEVs have proven to induce cellular differentiation, enhancing musculoskeletal or neural regeneration. However, the obtention and characterization of pEVs is widely heterogeneous and differs from the recommendations of the International Society for Extracellular Vesicles. Therefore, in this review, we aim to present the main advances in the therapeutical use of pEVs in the regenerative medicine field while highlighting the isolation and characterization steps followed. The main goal of this review is to portray the studies performed in order to enhance the translation of the pEVs research into feasible therapeutical applications.en
dc.description.sponsorshipThis research was funded by Instituto de Salud Carlos III, co-funded by the ESF European Social Fund and the ERDF European Regional Development Fund (projects PI17/01605 and PI20/00127) and the Direccio General d'Investigacio, Conselleria d'Investigacio, Govern Balear (contract to M.A.R.; FPI/2046/2017) and the Institut d'Investigacio Sanitaria de les Illes Balears (contract to M.A.F.G; through the PROGRAMA JUNIOR del proyecto TALENT PLUS, construyendo SALUD, generando VALOR (JUNIOR01/18), financed by the sustainable tourism tax of the Balearic Islands.es_ES
dc.format.number16es_ES
dc.format.page8580es_ES
dc.format.volume22es_ES
dc.identifier.citationAntich-Rossello M, Forteza-Genestra MA, Monjo M, Ramis JM. Platelet-Derived Extracellular Vesicles for Regenerative Medicine. Int J Mol Sci. 2021 Aug;22(16):8580.en
dc.identifier.doi10.3390/ijms22168580
dc.identifier.e-issn1422-0067es_ES
dc.identifier.journalInternational Journal of Molecular Scienceses_ES
dc.identifier.otherhttps://hdl.handle.net/20.500.13003/19750
dc.identifier.pubmedID34445286es_ES
dc.identifier.puiL2013331979
dc.identifier.scopus2-s2.0-85112114391
dc.identifier.urihttps://hdl.handle.net/20.500.12105/23297
dc.identifier.wos689124000001
dc.language.isoengen
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)
dc.relation.publisherversionhttps://dx.doi.org/10.3390/ijms22168580en
dc.rights.accessRightsopen accessen
dc.rights.licenseAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectExtracellular vesicles
dc.subjectExosomes
dc.subjectPlatelets
dc.subjectRegenerative medicine
dc.subject.decsAnimales*
dc.subject.decsPlaquetas*
dc.subject.decsHumanos*
dc.subject.decsMedicina Regenerativa*
dc.subject.decsVesículas Extracelulares*
dc.subject.decsCicatrización de Heridas*
dc.subject.decsChoque Hemorrágico*
dc.subject.meshWound Healing*
dc.subject.meshExtracellular Vesicles*
dc.subject.meshAnimals*
dc.subject.meshBlood Platelets*
dc.subject.meshHumans*
dc.subject.meshRegenerative Medicine*
dc.subject.meshShock, Hemorrhagic*
dc.titlePlatelet-Derived Extracellular Vesicles for Regenerative Medicineen
dc.typereview articleen
dspace.entity.typePublication
relation.isPublisherOfPublication30293a55-0e53-431f-ae8c-14ab01127be9
relation.isPublisherOfPublication.latestForDiscovery30293a55-0e53-431f-ae8c-14ab01127be9

Files

Collections

IdisBa - Instituto de Investigación Sanitaria Illes Balears (Baleares)