Publication: The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990-2019: Findings from the Global Burden of Disease Study 2019
| dc.contributor.author | Castelpietra, Giulio | |
| dc.contributor.author | Skrindo Knudsen, Ann Kristin | |
| dc.contributor.author | Agardh, Emilie E | |
| dc.contributor.author | Armocida, Benedetta | |
| dc.contributor.author | Beghi, Massimiliano | |
| dc.contributor.author | Moesgaard Iburg, Kim | |
| dc.contributor.author | Logroscino, Giancarlo | |
| dc.contributor.author | Ma, Rui | |
| dc.contributor.author | Starace, Fabrizio | |
| dc.contributor.author | Steel, Nicholas | |
| dc.contributor.author | Addolorato, Giovanni | |
| dc.contributor.author | Andrei, Catalina Liliana | |
| dc.contributor.author | Andrei, Tudorel | |
| dc.contributor.author | Ayuso-Mateos, José Luis | |
| dc.contributor.author | Banach, Maciej | |
| dc.contributor.author | Bärnighausen, Till Winfried | |
| dc.contributor.author | Barone-Adesi, Francesco | |
| dc.contributor.author | Srikanth Bhagavathula, Akshaya | |
| dc.contributor.author | Carvalho, Félix | |
| dc.contributor.author | Carvalho, Márcia | |
| dc.contributor.author | Singh Chandan, Joht | |
| dc.contributor.author | Kumar Chattu, Vijay | |
| dc.contributor.author | Couto, Rosa A S | |
| dc.contributor.author | Cruz-Martins, Natália | |
| dc.contributor.author | Dargan, Paul I | |
| dc.contributor.author | Deuba, Keshab | |
| dc.contributor.author | Dias-da-Silva, Diana | |
| dc.contributor.author | Fagbamigbe, Adeniyi Francis | |
| dc.contributor.author | Fernandes, Eduarda | |
| dc.contributor.author | Ferrara, Pietro | |
| dc.contributor.author | Fischer, Florian | |
| dc.contributor.author | Andras Gaal, Peter | |
| dc.contributor.author | Gialluisi, Alessandro | |
| dc.contributor.author | Haagsma, Juanita A | |
| dc.contributor.author | Haro, Josep Maria | |
| dc.contributor.author | Hasan, M Tasdik | |
| dc.contributor.author | Hasan, Syed Shahzad | |
| dc.contributor.author | Hostiuc, Sorin | |
| dc.contributor.author | Iacoviello, Licia | |
| dc.contributor.author | Iavicoli, Ivo | |
| dc.contributor.author | Jamshidi, Elham | |
| dc.contributor.author | Jonas, Jost B | |
| dc.contributor.author | Joo, Tamas | |
| dc.contributor.author | Jozwiak, Jacek Jerzy | |
| dc.contributor.author | Katikireddi, Srinivasa Vittal | |
| dc.contributor.author | Kauppila, Joonas H | |
| dc.contributor.author | Khan, Moien A B | |
| dc.contributor.author | Kisa, Adnan | |
| dc.contributor.author | Kisa, Sezer | |
| dc.contributor.author | Kivimäki, Mika | |
| dc.contributor.author | Koly, Kamrun Nahar | |
| dc.contributor.author | Koyanagi, Ai | |
| dc.contributor.author | Kumar, Manasi | |
| dc.contributor.author | Lallukka, Tea | |
| dc.contributor.author | Langguth, Berthold | |
| dc.contributor.author | Ledda, Caterina | |
| dc.contributor.author | Lee, Paul H | |
| dc.contributor.author | Lega, Ilaria | |
| dc.contributor.author | Linehan, Christine | |
| dc.contributor.author | Loureiro, Joana A | |
| dc.contributor.author | Madureira-Carvalho, Áurea M | |
| dc.contributor.author | Martinez-Raga, Jose | |
| dc.contributor.author | Mathur, Manu Raj | |
| dc.contributor.author | McGrath, John J | |
| dc.contributor.author | Mechili, Enkeleint A | |
| dc.contributor.author | Mentis, Alexios-Fotios A | |
| dc.contributor.author | Mestrovic, Tomislav | |
| dc.contributor.author | Miazgowski, Bartosz | |
| dc.contributor.author | Mirica, Andreea | |
| dc.contributor.author | Mirijello, Antonio | |
| dc.contributor.author | Moazen, Babak | |
| dc.contributor.author | Mohammed, Shafiu | |
| dc.contributor.author | Mulita, Francesk | |
| dc.contributor.author | Nagel, Gabriele | |
| dc.contributor.author | Negoi, Ionut | |
| dc.contributor.author | Negoi, Ruxandra Irina | |
| dc.contributor.author | Ebuka Nwatah, Vincent | |
| dc.contributor.author | Padron-Monedero, Alicia | |
| dc.contributor.author | Panda-Jonas, Songhomitra | |
| dc.contributor.author | Pardhan, Shahina | |
| dc.contributor.author | Pasovic, Maja | |
| dc.contributor.author | Patel, Jay | |
| dc.contributor.author | Petcu, Ionela-Roxana | |
| dc.contributor.author | Pinheiro, Marina | |
| dc.contributor.author | Pollok, Richard Charles G | |
| dc.contributor.author | Postma, Maarten J | |
| dc.contributor.author | Laith Rawaf, David | |
| dc.contributor.author | Rawaf, Salman | |
| dc.contributor.author | Romero-Rodríguez, Esperanza | |
| dc.contributor.author | Ronfani, Luca | |
| dc.contributor.author | Sagoe, Dominic | |
| dc.contributor.author | Sanmarchi, Francesco | |
| dc.contributor.author | Schaub, Michael P | |
| dc.contributor.author | Tadesse Sharew, Nigussie | |
| dc.contributor.author | Shiri, Rahman | |
| dc.contributor.author | Shokraneh, Farhad | |
| dc.contributor.author | Sigfusdottir, Inga Dora | |
| dc.contributor.author | Silva, João Pedro | |
| dc.contributor.author | Silva, Renata | |
| dc.contributor.author | Socea, Bogdan | |
| dc.contributor.author | Szócska, Miklós | |
| dc.contributor.author | Tabarés-Seisdedos, Rafael | |
| dc.contributor.author | Torrado, Marco | |
| dc.contributor.author | Tovani-Palone, Marcos Roberto | |
| dc.contributor.author | Vasankari, Tommi Juhani | |
| dc.contributor.author | Veroux, Massimiliano | |
| dc.contributor.author | Viner, Russell M | |
| dc.contributor.author | Werdecker, Andrea | |
| dc.contributor.author | Winkler, Andrea Sylvia | |
| dc.contributor.author | Hay, Simon I | |
| dc.contributor.author | Ferrari, Alize J | |
| dc.contributor.author | Naghavi, Mohsen | |
| dc.contributor.author | Allebeck, Peter | |
| dc.contributor.author | Monasta, Lorenzo | |
| dc.contributor.funder | Bill & Melinda Gates Foundation | |
| dc.date.accessioned | 2023-02-27T13:35:38Z | |
| dc.date.available | 2023-02-27T13:35:38Z | |
| dc.date.issued | 2022-04-01 | |
| dc.description.abstract | Background: Mental health is a public health issue for European young people, with great heterogeneity in resource allocation. Representative population-based studies are needed. The Global Burden of Disease (GBD) Study 2019 provides internationally comparable information on trends in the health status of populations and changes in the leading causes of disease burden over time. Methods: Prevalence, incidence, Years Lived with Disability (YLDs) and Years of Life Lost (YLLs) from mental disorders (MDs), substance use disorders (SUDs) and self-harm were estimated for young people aged 10-24 years in 31 European countries. Rates per 100,000 population, percentage changes in 1990-2019, 95% Uncertainty Intervals (UIs), and correlations with Sociodemographic Index (SDI), were estimated. Findings: In 2019, rates per 100,000 population were 16,983 (95% UI 12,823 - 21,630) for MDs, 3,891 (3,020 - 4,905) for SUDs, and 89·1 (63·8 - 123·1) for self-harm. In terms of disability, anxiety contributed to 647·3 (432-912·3) YLDs, while in terms of premature death, self-harm contributed to 319·6 (248·9-412·8) YLLs, per 100,000 population. Over the 30 years studied, YLDs increased in eating disorders (14·9%;9·4-20·1) and drug use disorders (16·9%;8·9-26·3), and decreased in idiopathic developmental intellectual disability (-29·1%;23·8-38·5). YLLs decreased in self-harm (-27·9%;38·3-18·7). Variations were found by sex, age-group and country. The burden of SUDs and self-harm was higher in countries with lower SDI, MDs were associated with SUDs. Interpretation: Mental health conditions represent an important burden among young people living in Europe. National policies should strengthen mental health, with a specific focus on young people. | es_ES |
| dc.description.peerreviewed | Sí | es_ES |
| dc.description.sponsorship | TW Bärnighausen was supported by the Alexander von Humboldt Foundation through the Alexander von Humboldt Professor award, funded by the German Federal Ministry of Education and Research. F Carvalho acknowledges support from Fundaçao para a Ciência e a Tecnologia (FCT), I.P., in the scope of the project UIDP/04378/2020 and UIDB/04378/2020 of the Research Unit on Applied Molecular Biosciences - UCI-BIO and the project LA/P/0140/2020 of the Associate Laboratory Institute for Health and Bioeconomy - i4HB; FCT/MCTES (Ministério da Ciência, Tecnologia e Ensino Superior) through the project UIDB/50006/2020. M Carvalho acknowledges the support from FCT in the scope of the project UIDP/04378/2020 and UIDB/04378/2020 of UCIBIO and the project LA/P/0140/2020 of i4HB. J S Chandan is funded on a lectureship post by the National Institute of Health Research (NIHR) and has been awarded funds from the NIHR and the Youth Endowment Fund. S Dias da Silva acknowledges the projects UIDP/04378/2021 and UIDB/04378/2021 of the Research Unit on Applied Molecular Biosciences−UCIBIO; the project LA/P/0140/2021 of the Associate Laboratory Institute for Health and Bioeconomy−i4HB; and TOXRUN − Toxicology Research Unit, University Institute of Health Sciences, IUCS-CESPU, Portugal. A J Ferrari is supported by a National Health and Medical Research Council Early Career Fellowship Grant APP1121516 and is employed by the Queensland Centre for Mental Health Research which receives core funding from the Queensland Department of Health. S V Katikireddi would like to acknowledge funding from a NRS Senior Clinical Fellowship (SCAF/15/02), the Medical Research Council (MC_UU_00022/2) and the Scottish Government Chief Scientist Office (SPHSU17). J H Kauppila reports research grants from Sigrid Juselius Foundation and the Finnish Cancer Foundation. M Kivimaki was supported by the Wellcome Trust (221854/Z/20/Z) and the Medical Research Council, UK (MR/R024227/1, MR/S011676/1). M Kumar would like to acknowledge funding support from K43 TW010716-04/NIH Fogarty International Centre. T Lallukka is supported by the Social Insurance Institution of Finland (grant 29/26/2020). J A Loureiro was supported by Fundaçao para a Ciência e Técnologia (FCT) under the Scientific Employment Stimulus [CEECINST/00049/2018]. J J McGrath was supported by the Danish National Research Foundation (Niels Bohr Professorship), and is employed by The Queensland Centre for Mental Health Research which receives core funding from the Queens land Health. A-F A Mentis would like to acknowledge funding ‘MilkSafe: A novel pipeline to enrich formula milk using omics technologies’, a research co-financed by the European Regional Development Fund of the European Union and Greek national funds through the Operational Program Competitiveness, Entrepreneurship and Innovation, under the call RESEARCH - CREATE - INNOVATE (project code: T2EDK-02222), as well as from ELIDEK (Hellenic Foundation for Research and Innovation, MIMS-860) both outside the submitted work. J P Silva acknowledges support, through Portuguese national funds via FCT/MCTES, from grants number UIDP/04378/2021 and UIDB/04378/2021 of the Research Unit on Applied Molecular Biosciences (UCIBIO), and LA/P/0140/2021 of the Associate Laboratory Institute for Health and Bioeconomy (i4HB). | es_ES |
| dc.format.page | 100341 | es_ES |
| dc.format.volume | 16 | es_ES |
| dc.identifier.citation | Lancet Reg Health Eur 2022 Apr 1;16:100341. | es_ES |
| dc.identifier.doi | 10.1016/j.lanepe.2022.100341 | es_ES |
| dc.identifier.e-issn | 2666-7762 | es_ES |
| dc.identifier.journal | The Lancet regional health. Europe | es_ES |
| dc.identifier.pubmedID | 35392452 | es_ES |
| dc.identifier.uri | http://hdl.handle.net/20.500.12105/15547 | |
| dc.language.iso | eng | es_ES |
| dc.publisher | Elsevier | |
| dc.relation.publisherversion | https://doi.org/10.1016/j.lanepe.2022.100341 | es_ES |
| dc.repisalud.centro | ISCIII::Escuela Nacional de Sanidad | es_ES |
| dc.repisalud.institucion | ISCIII | es_ES |
| dc.rights.accessRights | open access | es_ES |
| dc.rights.license | Atribución 4.0 Internacional | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
| dc.subject | Young people | es_ES |
| dc.subject | Mental health | es_ES |
| dc.subject | Mental disorders | es_ES |
| dc.subject | Self-harm | es_ES |
| dc.subject | Substance use | es_ES |
| dc.subject | Europe | es_ES |
| dc.title | The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990-2019: Findings from the Global Burden of Disease Study 2019 | es_ES |
| dc.type | research article | es_ES |
| dc.type.hasVersion | VoR | es_ES |
| dspace.entity.type | Publication | |
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