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A novel community driven software for functional enrichment analysis of extracellular vesicles data

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dc.contributor.authorPathan, Mohashin
dc.contributor.authorKeerthikumar, Shivakumar
dc.contributor.authorChisanga, David
dc.contributor.authorAlessandro, Riccardo
dc.contributor.authorAng, Ching-Seng
dc.contributor.authorAskenase, Philip
dc.contributor.authorBatagov, Arsen O
dc.contributor.authorBenito-Martin, Alberto
dc.contributor.authorCamussi, Giovanni
dc.contributor.authorClayton, Aled
dc.contributor.authorCollino, Federica
dc.contributor.authorDi Vizio, Dolores
dc.contributor.authorFalcon-Perez, Juan Manuel
dc.contributor.authorFonseca, Pedro
dc.contributor.authorFonseka, Pamali
dc.contributor.authorFontana, Simona
dc.contributor.authorGho, Yong Song
dc.contributor.authorHendrix, An
dc.contributor.authorHoen, Esther Nolte-'t
dc.contributor.authorIraci, Nunzio
dc.contributor.authorKastaniegaard, Kenneth
dc.contributor.authorKislinger, Thomas
dc.contributor.authorKowal, Joanna
dc.contributor.authorKurochkin, Igor V
dc.contributor.authorLeonardi, Tommaso
dc.contributor.authorLiang, Yaxuan
dc.contributor.authorLlorente, Alicia
dc.contributor.authorLunavat, Taral R
dc.contributor.authorMaji, Sayantan
dc.contributor.authorMonteleone, Francesca
dc.contributor.authorØverbye, Anders
dc.contributor.authorPanaretakis, Theocharis
dc.contributor.authorPatel, Tushar
dc.contributor.authorPeinado Selgas, Hector
dc.contributor.authorPluchino, Stefano
dc.contributor.authorPrincipe, Simona
dc.contributor.authorRonquist, Goran
dc.contributor.authorRoyo, Felix
dc.contributor.authorSahoo, Susmita
dc.contributor.authorSpinelli, Cristiana
dc.contributor.authorStensballe, Allan
dc.contributor.authorThéry, Clotilde
dc.contributor.authorvan Herwijnen, Martijn J C
dc.contributor.authorWauben, Marca
dc.contributor.authorWelton, Joanne L
dc.contributor.authorZhao, Kening
dc.contributor.authorMathivanan, Suresh
dc.contributor.funderAustralian Research Council
dc.contributor.funderUnited States Department of Health and Human Services
dc.date.accessioned2019-09-30T10:09:17Z
dc.date.available2019-09-30T10:09:17Z
dc.date.issued2017-05-26
dc.description.abstractBioinformatics tools are imperative for the in depth analysis of heterogeneous high-throughput data. Most of the software tools are developed by specific laboratories or groups or companies wherein they are designed to perform the required analysis for the group. However, such software tools may fail to capture "what the community needs in a tool". Here, we describe a novel community-driven approach to build a comprehensive functional enrichment analysis tool. Using the existing FunRich tool as a template, we invited researchers to request additional features and/or changes. Remarkably, with the enthusiastic participation of the community, we were able to implement 90% of the requested features. FunRich enables plugin for extracellular vesicles wherein users can download and analyse data from Vesiclepedia database. By involving researchers early through community needs software development, we believe that comprehensive analysis tools can be developed in various scientific disciplines.es_ES
dc.description.peerreviewedSíes_ES
dc.description.sponsorshipWe would like to thank Tejaswee P. Shah for her valuable input in the development of FunRich. We would like to thank Jan Lotvall for helping us in this effort by circulating the email within his group. We thanks many other users who requested for features/changes in FunRich though the e-mail and the online forum. Suresh Mathivanan is supported by Australian Research Council DECRA (DE150101777) and Award U54- DA036134 supported by the NIH Common Fund through the Office of Strategic Coordination/Office of the NIH Director.The funders had no role in study design, data collection andanalysis, decision to publish, or preparation of the manuscript.es_ES
dc.format.number1es_ES
dc.format.page1321455es_ES
dc.format.volume6es_ES
dc.identifier.citationJ Extracell Vesicles. 2017 ;6(1):1321455es_ES
dc.identifier.doi10.1080/20013078.2017.1321455es_ES
dc.identifier.issn2001-3078es_ES
dc.identifier.journalJournal of extracellular vesicleses_ES
dc.identifier.pubmedID28717418es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/8389
dc.language.isoenges_ES
dc.publisherTaylor & Francis
dc.relation.publisherversionhttps://doi.org/10.1080/20013078.2017.1321455es_ES
dc.repisalud.institucionCNIOes_ES
dc.repisalud.orgCNIOCNIO::Grupos de investigación::Grupo de Microambiente y Metástasises_ES
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAtribución-NoComercial-CompartirIgual 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectExtracellular vesicleses_ES
dc.subjectFunRiches_ES
dc.subjectBioinformaticses_ES
dc.titleA novel community driven software for functional enrichment analysis of extracellular vesicles dataes_ES
dc.typejournal articlees_ES
dc.type.hasVersionVoRes_ES
dspace.entity.typePublication
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