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In vitro evaluation of the antitumoral and antiangiogenic effects of extracts from Spondias mombin L. leaves

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dc.contributor.authorRey-Blanes, Cristina
dc.contributor.authorPérez-Portero, Yalina
dc.contributor.authorMorris-Quevedo, Humberto J.
dc.contributor.authorCasas, Virginia
dc.contributor.authorAbdala, Roberto
dc.contributor.authorQuesada, Ana R.
dc.contributor.authorMartínez-Poveda, Beatriz
dc.contributor.authorMedina, Miguel Ángel
dc.contributor.authoraffiliation[Rey-Blanes,C; Quesada,AR; Martínez-Poveda;B; Medina,MA] Universidad de Málaga, Andalucía Tech, Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Málaga, Spain. [Pérez-Portero,Y] Facultad de Ciencias Naturales y Exactas, Departamento de Biología, Universidad de Oriente, Santiago de Cuba, Cuba. [Morris-Quevedo,HJ] Centro de Estudios de Biotecnología Industrial (CEBI), Universidad de Oriente, Santiago de Cuba, Cuba. [Casas,V; Abdala,R] Universidad de Málaga, Andalucía Tech, Departamento de Ecología y Geología, Facultad de Ciencias, Málaga, Spain. [Abdala,R] IBYDA (Institute of Blue Biotechnology and Development), Málaga, Spain. [Quesada,AR; Martínez-Poveda;B; Medina,MA] IBIMA (Biomedical Research Institute of Málaga), Málaga, Spain. [Quesada,AR; Medina,MA] CIBER de Enfermedades Raras (CIBERER), Málaga, Spain. [Martínez-Poveda.B] CIBER de Enfermedades Vasculares (CIBERCV), Madrid, Spain.
dc.date.accessioned2024-02-12T19:47:45Z
dc.date.available2024-02-12T19:47:45Z
dc.date.issued2020-11
dc.description.abstractThe traditional ethnobotanic and pharmacologic use of Spondias mombin L. samples includes a wide range of applications. In the present study, new antiangiogenic and antitumor effects of two types of extracts from Spondias mombin L. leaves have been demonstrated by using a number of in vitro assays in both endothelial and human cancer and non cancer cells.
dc.description.sponsorshipThis work was supported by grants PID2019-105010RB-I00 (Spanish Ministry of Science) , Innovation and Universities is the Spanish Ministry of Science and Innovation, UMA18-FEDERJA-220 (Andalusian Government and FEDER) and funds from group BIO 267 (Andalusian Government), as well as funds from “Plan Propio de Investigación y Transferencia” (U. Málaga). The “CIBER de Enfermedades Raras” and CIBERCV are an initiative from the ISCIII (Spain). The funders had no role in the study design, data collection and analysis, decision to publish or preparation of the manuscript.
dc.identifier.doi10.1016/j.biopha.2020.110716
dc.identifier.e-issn1950-6007es_ES
dc.identifier.issn0753-3322
dc.identifier.journalBiomedicine & Pharmacotherapyes_ES
dc.identifier.otherhttp://hdl.handle.net/10668/3489
dc.identifier.pubmedID32920516es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/18143
dc.language.isoeng
dc.publisherElsevier
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0753332220309094?via%3Dihubes
dc.rights.accessRightsopen accesses_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectSpondias mombin
dc.subjectAngiogenesis
dc.subjectAntiangiogenic effects
dc.subjectAntitumor effects
dc.subjectInhibidores de la angiogénesis
dc.subjectAnacardiaceae
dc.subjectLínea celular tumoral
dc.subjectHojas de la planta
dc.subject.meshAngiogenesis Inhibitors
dc.subject.meshAntineoplastic Agents, Phytogenic
dc.subject.meshCell Cycle
dc.subject.meshCell Line, Tumor
dc.subject.meshCell Movement
dc.subject.meshCell Survival
dc.subject.meshEndothelial Cells
dc.subject.meshHumans
dc.subject.meshPlant Extracts
dc.subject.meshPlant Leaves
dc.subject.meshAnacardiaceae
dc.titleIn vitro evaluation of the antitumoral and antiangiogenic effects of extracts from Spondias mombin L. leaves
dc.typeresearch article
dc.type.hasVersionVoR
dspace.entity.typePublication
relation.isPublisherOfPublication7d471502-7bd5-4f7a-90a4-8274382509ef
relation.isPublisherOfPublication.latestForDiscovery7d471502-7bd5-4f7a-90a4-8274382509ef

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