Extracellular cysteine disulfide bond break at Cys122 disrupts PIP2-dependent Kir2.1 channel function and leads to arrhythmias in Andersen-Tawil Syndrome

Cruz, Francisco M.Macias, AlvaroMoreno-Manuel, Ana I.Gutiérrez, Lilian K.Vera-Pedrosa, María LinarejosMartinez-Carrascoso, IsabelPérez, Patricia SánchezRuiz Robles, Juan ManuelBermúdez-Jiménez, Francisco JDíaz-Agustín, AitorMartínez de Benito, FernandoSantiago, Salvador AriasBraza-Boils, AitanaMartín-Martínez, MercedesGutierrez-Rodríguez, MartaBernal, Juan A.Zorio, EstherJiménez-Jaimez, JuanJalife, Jose2023-12-012023-12-012023bioRxiv . 2023 Jun 8:2023.06.07.544151.http://hdl.handle.net/20.500.12105/16742engSMURhttp://creativecommons.org/licenses/by-sa/4.0/Extracellular cysteine disulfide bond break at Cys122 disrupts PIP2-dependent Kir2.1 channel function and leads to arrhythmias in Andersen-Tawil SyndromeAtribución-CompartirIgual 4.0 Internacional10.1101/2023.06.07.544151open access