Dual use of antifungals in medicine and agriculture: How do we help prevent resistance developing in human pathogens?

Verweij, Paul EArendrup, Maiken CavlingAlastruey-Izquierdo, AnaGold, Jeremy A WLockhart, Shawn RChiller, TomWhite, P Lewis2023-05-082023-05-082022-12Drug Resist Updat. 2022 Dec;65:100885.http://hdl.handle.net/20.500.12105/16006Azole resistance in Aspergillus fumigatus is a One Health resistance threat, where azole fungicide exposure compromises the efficacy of medical azoles. The use of the recently authorized fungicide ipflufenoquin, which shares its mode-of-action with a new antifungal olorofim, underscores the need for risk assessment for dual use of antifungals.engVoRhttp://creativecommons.org/licenses/by/4.0/Aspergillus fumigatusDHODH inhibitorOne HealthOlorofimTriazole resistanceAntifungal AgentsFungicides, IndustrialHumansDrug Resistance, FungalAzolesAspergillus fumigatusAgricultureMicrobial Sensitivity TestsDual use of antifungals in medicine and agriculture: How do we help prevent resistance developing in human pathogens?Atribución 4.0 Internacional362831876510088510.1016/j.drup.2022.1008851532-2084Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapyopen access